Into the form of capsules or similar small containers for oral use (A61J3/07)

ethod of producing nanocapules of l-arginine // 2627819
FIELD: nanotechnology.SUBSTANCE: method is characterized in that L-arginine is slowly added to a suspension of carrageenan in butyl alcohol in the presence of 0.01 E472c preparation as a surfactant with stirring at 1300 rpm. Then 5 ml of hexane are poured, the resulting suspension of the nanocapsules is filtered off and dried at room temperature. The mass ratio core: the shell is 1:3 or 1:1.EFFECT: simplification and acceleration of the process of obtaining nanocapsules.3 ex

ethod of producing nanocapule of dry extract of briar in agar-agar // 2627585
FIELD: nanotechnology.SUBSTANCE: dry briar extract is slowly added to the agar-agar suspension in butanol in the presence of E472c as a surfactant with stirring at 1000 rpm. Then hexane is poured. After that, the precipitate is filtered off and dried at room temperature, the ratio of dry extract of briar to agar-agar is 1:1, 1:3 or 5:1.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses during the nanocapsules production.3 dwg, 4 ex

ethod of producing nanocapules of cyclophosphamide-lens // 2627584
FIELD: nanotechnology.SUBSTANCE: method of obtaining cyclophosphamide-LENS nanocapsules is characterized in that 0.5 g cyclophosphamide-LENS is slowly added to the suspension 0.1 g sodium alginate in butanol in the presence of 50 mg of E472c preparation as a surfactant with stirring at 1000 rpm, then 5 ml of diethyl ether are poured, the precipitate is filtered off and dried at room temperature.EFFECT: simplification and acceleration of nanocapsule production of cyclophosphamide-LENS, weight yield increase.1 dwg, 3 ex

ethod of obtaining nanocapsules of vera-ifosphamide in sodium alginate // 2627583
FIELD: nanotechnology.SUBSTANCE: vera-ifosphamide is slowly added to a suspension of sodium alginate in petroleum ether in the presence of E472c preparation as a surfactant with stirring at 1000 rpm, then methylene chloride is poured, the precipitate is filtered off and dried at room temperature. The mass ratio core: the envelope in nanocapsules is 5:1 or 1:1.EFFECT: acceleration and simplification of the process of obtaining the vera-ifosphamide nanocapsules, increasing their yield by mass.1 dwg, 3 ex

ethod of producing nanocapules of chloralhydrate in kappa-carraginane // 2627581
FIELD: nanotechnology.SUBSTANCE: chloral hydrate powder is added to a suspension of kappa-carrageenan in butanol and 0.01 g preparation E472c, used as a surfactant. Then 10 ml of methylene chloride is added, the resulting nanocapsule suspension is filtered off and dried. The mass ratio core: the shell in nanocapsules is 1:3 or 1:1.EFFECT: acceleration and simplification of the process of obtaining nanocapsules of chloralhydrate, and also increasing their yield by mass.1 dwg, 3 ex
ethod of obtaining nanocapules of antibiotics of tetracyclin row in konjac gum // 2627580
FIELD: nanotechnology.SUBSTANCE: antibiotics are selected from tetracycline, dioxycycline, minocycline, when the method is applied to a suspension of konjac gum in butanol and 0.01 g of E472c preparation as a surfactant, an antibiotic powder is added, then petroleum ether is added dropwise, which is used as a precipitant. The ratio of the amounts of antibiotic to the amount of konjac gum is 1:1, 1:3, 1:5 or 5:1, the resulting suspension of nanocapsules is filtered off and dried.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses during the nanocapsules production.4 dwg, 11 ex
ethod of obtaining nanocapules of metal salts in carraginan // 2627578
FIELD: nanotechnology.SUBSTANCE: carraginan is used as the nanocapsule shell, and the metal salt is used as the core for the mass ratio of the core: shell 1:3. The metal salt is added to a suspension of carraginan in ethanol containing the E472c preparation as a surfactant, with stirring at 1200 rpm, then methylene chloride is poured, the resulting suspension is filtered off and dried at room temperature.EFFECT: simplification and acceleration of the process of obtaining nanocapsules.11 ex
ethod of producing nanocapules of metal salts in sodium alginate // 2627577
FIELD: nanotechnology.SUBSTANCE: sodium alginate is used as the nanocapsule coating, and the metal salt is used as the core for the core to shell: 1:3 shell weight ratio, while the metal salt is added to a suspension of sodium alginate in butanol containing the E472c preparation as a surfactant with stirring 1200 rpm, then petroleum ether is poured, the resulting suspension is filtered off and dried at room temperature.EFFECT: simplification and acceleration of the process of obtaining nanocapsules.11 ex

ethod of producing nanocapsules of biopaga-d mixture with diamond green // 2626836
FIELD: nanotechnology.SUBSTANCE: method of obtaining nanocapsules of a biopag-D mixture with a diamond green is proposed. The way is that to 2.5 grams Biopag-D is added 2.5 ml of brilliant green, the resulting mixture is added to the suspension 2.5 grams or 7.5 g Apple or citrus pectin in petroleum ether and 0.05 g Preparation E472c as a surfactant, the obtained mixture is put on a magnetic stirrer and stirring is carried out, the precipitated nanocapsule suspension is filtered on a 16 grade porous Schott filter, washed with petroleum ether, dried in a desiccator over calcium chloride. A distinctive feature of the proposed method is the use as an envelope of nanocapsules of apple or citrus pectins.EFFECT: nanocapsules manufacture process simplification and acceleration and weight yield increase.2 dwg, 9 ex
ethod of betulin nanocapsules production // 2626508
FIELD: nanotechnology.SUBSTANCE: betulin is added to the suspension of agar-agar in petroleum ether in the presence of 0.01 g. of the surfactant E472c, wherein the core to shell weight ratio is 2:1, 1:1 or 1:3 when recalculating to dry matter, then, with stirring at 1300 rpm, ethyl acetate is added, the resulting suspension is filtered and dried at room temperature.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses during the nanocapsules production.3 ex
ethod of obtaining chloralhydrate nanocapsules in sodium alginate // 2626507
FIELD: nanotechnology.SUBSTANCE: into a slurry of sodium alginate in hexane and 0.01 g of E472c as a surfactant, chloral hydrate powder is added, then methyl ethyl ketone is added. The ratio of the amount of chloral hydrate and the amount of sodium alginate is 1:1 or 1:3, the resulting suspension is filtered off and dried.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses during the nanocapsules production.3 ex

ethod for producing sodium hydrogen carbonate nanocapsules in carrageenan // 2625764
FIELD: nanotechnology.SUBSTANCE: sodium bicarbonate is dispersed in carrageena suspension in petroleum ether with the presence of 0.01 g of E472c preparation as a surfactant with stirring at 1200 rpm, then methylene chloride is poured. The mass ratio of core: shell is 1:1, 1:2, 1:3 or 1:5 in terms of dry substance, the resulting suspension is filtered off and dried at room temperature.EFFECT: simplifying and accelerating the nanocapsule obtaining process, reducing the losses when obtaining nanocapsules.2 dwg, 5 ex

ethod of production of antiseptic dorogov's stimulator (ads) nanocapsules fraction 2 in carrageenan // 2625547
FIELD: nanotechnology.SUBSTANCE: invention relates to a method of production of antiseptic Dorogov's stimulator (ADS) nanocapsules 2 fraction in carrageenan. This method is characterized in that the ASD 2 fraction is dispersed in a solution of carrageenan in benzene in the presence of E472c preparation as a surfactant in stirring at 1,300 rpm, then 10 ml of sulphuric ether are added, the resulting suspension is filtered off and dried at room temperature. The mass ratio core: shell is 1:1, 1:3 or 3:1.EFFECT: simplification and acceleration of the process of producing the nanocapsules, as well as increase in their yield by weight.3 dwg, 4 ex

ethod for obtaining nanocapules of rosehip dry extract // 2625501
FIELD: food industry.SUBSTANCE: method is characterized by the fact that 1 g of dry rosehip extract is dispersed in the suspension of sodium alginate in benzene, containing 1 g or 3 g of said polymer, in the presence of 0.01 g of the preparation E472c as a surfactant with stirring at 1300 rpm, then 5 ml of acetonitrile are added, the precipitate formed is filtered off and dried at room temperature.EFFECT: simplifying and accelerating the process of obtaining rosehip extract nanocapsules, increasing their yield by weight.1 dwg, 4 ex

ethod of obtaining chia seeds nanocapules (salvia hispanica) in carageenan // 2624533
FIELD: nanotechnology.SUBSTANCE: method of obtaining chia seeds nanocapules (core) in a coat of carrageenan is described. According to the method, the chia seed powder is added to a suspension of carrageenan in benzene in the presence of 0.01 g E472c as surface-active substance. The mixture is then stirred at 1000 rpm, methylene chloride is added. The resulting suspension is filtered and dried at the room temperature. The ratio core:shell is 1:3 or 1:1.EFFECT: nanocapsules manufacture process simplification and acceleration and weight yield increase.1 dwg, 3 ex

ethod of obtaining chia seeds nanocapules (salvia hispanica) in konjac gum // 2624532
FIELD: nanotechnology.SUBSTANCE: chia seeds powder is slowly added to a suspension of konjac gum in benzene in the presence of 0.01 g E472c as a surfactant, and then stirred at 1000 r/min and the butyl chloride is poured, the resulting suspension is filtered and dried at room temperature, wherein the weight ratio of core: shell is 1:1 or 1:3.EFFECT: simplification and acceleration of chia seeds nanocapsule production, weight yield increase.1 dwg, 3 ex

ethod of obtaining chia seeds nanocapules (salvia hispanica) in alginate sodium // 2624531
FIELD: nanotechnology.SUBSTANCE: for shells of nanocapsules sodium alginate is used, and the chia seeds powder is slowly added to a suspension of sodium alginate in benzene in the presence of 0.01 g E472c as a surfactant, and then stirred at 1000 r/min and the carbon tetrachloride is poured, the resulting suspension is filtered and dried at room temperature, wherein the weight ratio of core: shell is 1:1 or 1:3.EFFECT: simplification and acceleration of nanocapsule production, weight yield increase.1 dwg, 3 ex

ethod for producing unabi nanocapsules in gellan gum // 2624530
FIELD: chemistry.SUBSTANCE: method is characterized in that 500 mg of Unabi fruit powder is dispersed into a suspension of 1.5 g of gellan gum in butanol in the presence of 0.01 g of E472c as a surfactant with stirring at 1300 rpm, then 10 ml of methylene chloride are added, the resulting suspension is filtered off and dried at room temperature.EFFECT: simplifying and accelerating the production process of unabi nanocapsules, increasing their yield by weight.1 dwg, 3 ex
Production method of metal oxides nanocapsules in carrageenan // 2622982
FIELD: nanotechnology.SUBSTANCE: metal oxides are selected from aluminium oxide, copper oxide(I), copper oxide (II), manganese oxide (IV), titanium oxide (IV), carrageenan is used as the shell. During the method execution 1 g of the metal oxide is slowly added to the 3 grams carrageenan suspension in petroleum ether in the presence of 0.01 g of the preparation E472c as the surfactant with stirring at 1200 rpm, wherein the core to shell weight ratio is 1: 3 when recalculated to dry matter, then 5 ml of acetone is added as the precipitator, the resulting suspension is filtered off and dried at room temperature.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses during the nanocapsules production.3 dwg, 6 ex
ethod for spinage dry extract nanocapules production // 2622752
FIELD: pharmacology.SUBSTANCE: 1 g of spinage dry extract is added to 1 g or 3 g of sodium alginate suspension in butanol containing 0.01 g of E472c preparation as a surfactant. Then, 5 ml of methylene chloride is added, the resulting nanocapsule suspension is filtered off, washed with methylene chloride and dried.EFFECT: simplification and acceleration of spinage dry extract nanocapsules obtaining process, increasing their yield by mass.1 dwg, 3 ex
ethod for producing nanocapules of betulin in gellan gum // 2622750
FIELD: nanotechnology.SUBSTANCE: method is characterized in that 100 mg of betulin powder is slowly added to a suspension of 100 mg or 300 mg of gellan gum in butanol in the presence of 0.01 g of E472c with stirring at 1300 rpm, then 3 ml of hexane are added, the resulting suspension is filtered and dried at room temperature.EFFECT: simplification and acceleration of betulin nanocapsule production, weight yield increase.1 dwg, 3 ex

ethod and device for manufacturing capsules // 2622749
FIELD: pharmacology.SUBSTANCE: method of manufacturing the capsule 12 for storing the substance 14 includes providing the first part 2 of the capsule, characterized by the presence of the closed end 5 and the opposite open end 6, providing the second part 4 of the capsule, characterized by the presence of the closed end 7 and the opposite open end 8, partial filling the first part 2 of the capsule with the substance 14, supporting the outer side 43 of the first part 2 of the capsule and supporting the inner side 102 of the second part 4 of the capsule at the overlapping capsule areas when inserting the closed end 7 of the second part 4 of the capsule into the open end 6 of the first part 2 of the capsule until the areas of the capsule parts overlap with each other to thereby block the open end 6 of the first part 2 of the capsule and to form a chamber 104 within which the substance 14 is stored. The group of inventions also relates to a device for the manufacture of said capsules.EFFECT: group of inventions prevents separation of capsule and eliminates deformation of the walls and open ends of the capsule.24 cl, 10 dwg

ethod and device for manufacturing capsules // 2622748
FIELD: pharmacology.SUBSTANCE: method of manufacturing the capsule 12 for storing material 14 in hermetical conditions includes providing the first part 2 of the capsule, providing the second part 4 of the capsule, filling the first part 2 of the capsule with substance 14, inserting the closed end 7 of the second part 4 of the capsule into the open end 6 of the first part 2 of the capsule so that the areas of the second part 4 and first part 2 of the capsule overlap each other to block the open end 6 of the first part of the capsule and limit the chamber 104, inside which the substance 14 is stored, and connecting the open ends 6,8 of the first part of the capsule and the second part of the capsule, which are levelled, with each other to seal the chamber. Thus, insertion of the closed end 7 of the second part 4 of the capsule takes place until the open ends of the first part and the second part of the capsule 6, 8 are levelled with each other. The group of inventions also relates to a device for the manufacture of said capsules.EFFECT: efficient sealing of the inner chamber of the capsule, obtaining capsules with chambers of equal volume, provision for more reliable maintaining of the shape of the capsules in processing and transportation.15 cl, 10 dwg

ethod for the production of metal oxides nanocapsule // 2622011
FIELD: nanotechnology.SUBSTANCE: metal oxides are selected from zinc oxide, copper oxide (I), copper oxide (II), alumina, manganese oxide (IV), titanium oxide (IV), while implementing the method, 1 g of metal oxide is slowly added to suspension of 3 grams of sodium alginate in petroleum ether in the presence of 0.01 g of preparation E472c as a surface-active agent while stirring at 1200 rpm, and core:shell mixing ratio on a dry basis is 1:3, then 5 ml of carbon tetrachloride are added, the resulting suspension is filtered and dried at room temperature.EFFECT: nanocapsules production process simplification and acceleration, reduction of losses in nanocapsules production.5 dwg, 7 ex

Hydrocortisone composition with controlled release // 2619869
FIELD: pharmacology.SUBSTANCE: invention relates to a pharmaceutical composition for oral administration, comprising a core containing hydrocortisone and a carrier, and a delayed release polymer layer in contact with the said core. The core contains microcrystalline cellulose in an amount of 75-85% by composition weight. The delayed release polymer is a mixture of a polymer (1) having a composition of poly(methacrylic acid, methyl methacrylate) at a ratio of 1:1, and a polymer (2) having a composition of poly(methacrylic acid, methyl methacrylate) at a ratio of 1:2. Polymers (1) and (2) are presented at a ratio of 1:4 and are taken in an amount of 6-7% by composition weight. Also a method for composition manufacture and its use for treating adrenal insufficiency is described.EFFECT: release of hydrocortisone in accordance with the circadian release of cortisol to reproduce natural cortisol release.39 cl, 7 dwg, 2 tbl, 4 ex

ethod for production of nanocapules of penicillin group medicine preparations in carraginan // 2618453
FIELD: pharmacology.SUBSTANCE: 0.01 g of E472c preparation is added to 0.5 g of carrageenan in hexane as a surfactant, 0.5 g of antibiotic powder is added to the resulting suspension in small portions, then 5 ml of butyl chloride is added, the resulting nanocapsule suspension is filtered off and dried at 25C.EFFECT: simplification and acceleration of penicillin group drugs nanocapsules obtaining process, increased yield by mass.4 dwg, 5 ex

ethod for group b vitamins nanocapules production in kappa-carrageenan // 2618449
FIELD: pharmacology.SUBSTANCE: kappa-carrageenan is used as an envelope, and group B vitamins are used as the core, at core: shell mass ratio of 1:3 or 1:1, while the vitamin is added to the kappa-carrageenan suspension in isopropyl alcohol in the presence of E472c preparation as a surfactant with stirring at 1300 rpm, petroleum ether is added, the resulting suspension is filtered off and dried at room temperature.EFFECT: acceleration and simplification of group B vitamins nanocapsules obtaining process, increased yield by mass.5 dwg, 11 ex

A method for producing nanocapsules of vitamins of the group b in the gellan gum // 2616514
FIELD: nanotechnology.SUBSTANCE: gellan gum is used as a casing, wherein the vitamin B group is added to a suspension of gellan gum in benzene in the presence E472s preparation as surfactant while stirring at 1300 rev/min, then added acetonitrile at a weight ratio of core: shell 1:3 or 1:1, the resulting suspension was filtered and dried at room temperature.EFFECT: nanocapsules manufacture process simplification, reduction of losses in the nanocapsules production, acceleration and weight yield increase.4 dwg, ex 11

Compositions and methods for myelofibrosis treatment // 2616262
FIELD: medicine, pharmacy.SUBSTANCE: capsule containing a mixture of a compound which is N-tert-butyl-3-[(5-methyl-2-{[4- (2-pyrrolidin-1-lethoxi)phenyl]amino} pyrimidin-4-yl)amino]benzenesulphonamide, or a pharmaceutically acceptable salt or hydrate thereof, microcrystalline cellulose and sodium stearyl fumarate. The mixture contains from 10 to 500 mg of the said compound. The weight ratio of the compound to microcrystalline cellulose in the mixture is within the range from 1:1.5 to 1:15. The amount of sodium stearyl fumarate in the mixture is 1% by weight of the capsule contents. A method of capsulesproduction, a method for myelofibrosis treatment and a kit for myelofibrosis treatment are also described. N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl] amino} pyrimidin-4-yl)amino]benzenesulphonamide medication provided as a capsule shows stability and instant release characteristics.EFFECT: invention describes a capsule for oral administration for treatment of myelofibrosis.38 cl, 18 dwg, 25 tbl, 6 ex

ethod of obtaining rosuvastatine nanocapsules in sodium alginate // 2615366
FIELD: nanotechnology.SUBSTANCE: method of obtaining the rosuvastatine nanocapsules is carried out as follows. Rosuvastatine is slowly added to the suspension of sodium alginate in hexane in the presence of 0.005 g of E472s drug, with stirring at 1000 rpm/sec. Then 3 ml of butyl chloride are poured. The resulting suspension is filtered and dried at the room temperature. The ratio of rosuvastatine: sodium alginate is 1:3 or 5:1.EFFECT: method as per the invention provides the simplification and acceleration of the nanocapsules obtaining process and the yield increase by weight.1 dwg, 3 ex

Stable pharmaceutical composition for oral administration comprising levocetirizine, or pharmaceutically acceptable salt thereof and montelukast or pharmaceutically acceptable salt thereof // 2614382
FIELD: medicine, pharmacy.SUBSTANCE: this present invention relfers to a pharmaceutical composition in the form of a capsule for oral administration for asthma or allergic rhinitis prevention or treatment. The composition comprises: (a) the first fraction of particles in the form of mini-pill comprising levocetirizine, or pharmaceutically acceptable salt thereof and organic acid; and (b) the second fraction of particles in the form of mini-pill comprising montelukast or pharmaceutically acceptable salt thereof. The organic acid is citric acid, tartaric acid, succinic acid or ascorbic acid. The organic acid is present in the amount of 100 parts by weight per 100 parts of levocetirizine. The said first and second particle fractions are physically separated and filled into the capsule. A method for pharmaceutical capsule composition production is also described. The pharmaceutical composition of this invention inhibits the production of related contaminants of levocetirizine and montelukast and provides good stability.EFFECT: invention expands the product range of drugs for allergic rhinitis or asthma prevention or treatment.9 cl, 3 dwg, 4 tbl, 6 ex

Process of getting rosemary nanocapsules in sodium alginate // 2613883
FIELD: nanotechnology.SUBSTANCE: for shells of nanocapsules sodium alginate is used, and the rosemary powder is slowly added to a suspension of sodium alginate in petroleum ether in the presence of 0.01 g E472c as a surfactant, and then stirred at 1000 r/min and the ethyl acetate is poured, the resulting suspension is filtered and dried at room temperature, wherein the weight ratio of core: shell in nanocapsules is 1:1 or 1:3.EFFECT: simplification and acceleration of the process of producing the nanocapsules of rosemary, as well as increase their yield by weight.1 dwg, 3 ex

ethod for production "ks" swine fever vaccine nanocapsules in sodium alginate // 2613795
FIELD: biotechnology.SUBSTANCE: method includes dilution of 55 mg of "KS" vaccine were dissolved in 3 ml of petroleum ether and dispersed into a sodium alginate suspension in petroleum ether containing 550 mg of this polymer in the presence of 60 mg of E472s preparation as surfactant while stirring at 1000 rpm, then 5 ml of ethyl acetate is added, the precipitate is filtered and dried at room temperature.EFFECT: simplification and acceleration of "KS" vaccine nanocapsules production process, increasing their output by weight.1 dwg, 1 tbl, 3 ex

ethod for praparing nanocapsules of medicinal plants having sedative effect // 2613761
FIELD: pharmacology.SUBSTANCE: invention relates to chemical and pharmaceutical industry, and is a method for preparing nanocapsules of the medicinal plants having a sedative effect, characterized in that the tinctures of valerian, motherwort and anomalous peony are added to the suspension of sodium carboxymethyl cellulose in acetone in the presence of 0.01 g of E472s preparation as a surfactant, while stirring at 1300 rev/min, the prepared suspension is filtered and dried at room temperature, wherein the ratio of core: shell in case of preparing the motherwort tincture nanocapsules is 1:3, 1:1, 5:1 or 1:5, in the case of preparing the valerian tincture nanocapsules is 1:3, 1:1, 5:1, 1:5, in the case of preparing the anomalous peony tincture nanocapsules is 1:3, 1:5.EFFECT: invention allows to simplify and accelerate the method of preparing the nanocapsules and to increase the weight yield.3 dwg, 11 ex

Production method of metronidazole nanocapsules in konjac gum // 2613108
FIELD: nanotechnology.SUBSTANCE: metronidazole powder is added to konjac gum suspension in butanol and 0.01g of E472s, used as a surface-active substance, then 10 ml of carbon tetrachloride is added, the resulting suspension of nanocapsules is filtered and dried off, at that the weight ratio of core: shell in nanocapsules is 1:3, 1:1, 1:5 or 5:1.EFFECT: metronidazole nanocapsules production process simplification and acceleration, and also the weight yield increase.2 dwg, 5 ex

ethod of production of sodium hydrogen carbonate nanocapsules // 2612348
FIELD: nanotechnology.SUBSTANCE: sodium hydrogencarbonate is added to sodium alginate suspension in petroleum ether with the presence of E472c as a surface-active substance during agitation of 1,200 rpm, then, 5 ml of carbon tetrachloride is added, whereupon, the core:shell mass ratio is 1:1, 1:2, 1:3 or 1:5 on conversion to dry substance; the obtained suspension is filtered and dried at room temperature.EFFECT: nanocapsules manufacture process simplification, reduction of losses in the nanocapsules production, acceleration and weight yield increase.2 dwg, 5 ex

ethod of producing nanocapsules of metal salts in agar-agar // 2612025
FIELD: nanotechnology.SUBSTANCE: method is characterized in that 100 mg of metal salt (potassium iodide, magnesium, zinc or calcium carbonate, calcium chloride) is dispersed into a suspension of 100 or 300 mg of agar-agar in benzene in the presence of 0.01 g of E472s preparation as a surface-active agent while stirring at 1200 rev/min, followed by pouring of 5 ml chloroform. The molar ratio of core: sheath ratio is 1:1 or 1:3, then the resulting suspension is filtered and dried at room temperature.EFFECT: nanocapsules manufacture process simplification and acceleration and weight yield increase.11 ex, 3 dwg

ethod of production of ecocide nanocapsules in sodium alginate // 2611369
FIELD: nanotechnology.SUBSTANCE: ecocide C is added portionwise is added to sodium alginate suspension in hexane and 0.01 g of E472s while stirring 1000 r/min and then methylene chloride is poured in, the obtained suspension is filtered and dried at room temperature. The mass ratio core:shell in nanocapsules is 1:3, 1:1, 1:5 or 5:1.EFFECT: nanocapsules of ecocide C manufacture process simplification and acceleration and weight yield increase.2 dwg, 5 ex

ethod of production of metronidazole nanocapsules in sodium alginate // 2611368
FIELD: nanotechnology.SUBSTANCE: metronidazole powder is added to sodium alginate suspension in hexane and 0.01 g of E472s then acetone is added, the obtained suspension is filtered and dried. The mass ratio core:shell in nanocapsules is 1:3, 1:1, 1:5 or 5:1.EFFECT: nanocapsules of metronidazole manufacture process simplification and acceleration and weight yield increase.1 dwg, 5 ex

ethod of producing of microcapsules of tetracycline antibiotics in sodium alginatemethod of producing of microcapsules of aminoglycoside antibiotics in sodium alginate // 2611367
FIELD: nanotechnology.SUBSTANCE: an antibiotic powder is added to sodium alginate suspension in petroleum ether and 0.01 g of E472s drug as a surface-active substance, then, 5 ml of carbon tetrachloride is added, the obtained suspension is filtered and dried. The mass ratio core:shell in nanocapsules is 1:3 or 1:1.EFFECT: nanocapsules of antibiotics manufacture process simplification and acceleration and weight yield increase.2 dwg, 11 ex
Drug based on tetrametiltetraazobitsiklooktandion and method for its production // 2611194
FIELD: pharmacy.SUBSTANCE: here is a description of dosage form of tetrametiltetraazobitsiklooktandion, additionally containing a filler, granulating agent, lubricant, disintegrant, flavoring agent in certain weight ratios. Methods of preparing of the said dosage form are also described.EFFECT: preparation of the dosage form without defects in manufacture and storage and with improved taste characteristics.11 cl, 3 tbl

ethod for producing nanocapsules containing biopag-d and brilliant green // 2609826
FIELD: chemistry.SUBSTANCE: brilliant green in the amount of 2.5 ml added to 2.5 g of biopag-D, the resulting mix is added to 2.5 g or 7.5 g of carboxymethyl cellulose suspension in petroleum ether and 0.05 g of surfactant E472; the resulting mix is stirred using a magnetic stirrer, the precipitated nanocapsules are filtered off, washed with petroleum ether and dried.EFFECT: accelerated and simplified process of pcoducing nanocapsules containing biopag-D and brilliant green, improved mass yield.1 dwg, 3 ex

ethod for obtaining nanocapsules of medications of penicillin goup in sodium alginate // 2609824
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to method for obtaining nanocapsules of medications of penicillin group, selected from ampicillin, sodium salt of benzylpenicillin or amoxicillin. The claimed method is characterised by the fact that 0.01 g of preparation E472c is added to 0.5 g of sodium algenate in petroleum ether as surface active substance, 0.5 g of antibiotic powder is added to obtained suspension in small portions, with the following addition of 5 ml of chloroform, obtained suspension of nanocapsules is filtered and dried.EFFECT: invention ensures simplification and acceleration of process of obtaining nanocapsules of penicillin group medications, as well as increase of their output by weight.3 dwg, 7 ex

ethod for producing ciprofloxacin hydrochloride nanocapsules // 2609742
FIELD: chemistry.SUBSTANCE: invention relates to a method for producing ciprofloxacin hydrochloride nanocapsules. According to the invention ciprofloxacin hydrochloride powder is added to the suspension of gellan gum in butanol and 0.01 g of E472c agent, followed by chloroform, and the resulting nanocapsule suspension is filtered and dried. The core : shell ratio in the nanocapsules was 1:3, 1:1, 1:5 or 5:1.EFFECT: quick and easy process of producing ciprofloxacin hydrochloride nanocapsules and increase of mass yield.1 dwg, 5 ex

ethod for production of "ks" vaccine nanocapsules from swine fever covered by sodium carboxymethylcellulose // 2609741
FIELD: medicine.SUBSTANCE: invention refers to the method for preparation of "KS" vaccine nanocapsules against swine fever. The peculiarity of the said method is that the "KS" vaccine is dissolved in petroleum ether, and then dispersed into a suspension of sodium carboxymethylcellulose in petroleum ether in the presence of E472s preparation as a surfactant while stirring 1000 rev/min, then butyl chloride is added, nanocapsules precipitation is filtered and dried at room temperature.EFFECT: invention provides simplification and acceleration of the production process of the "KS" vaccine nanocapsules, as well as increase of their yield by weight.1 dwg, 3 ex

ethod for preparation of nanocapsules of aminoglycoside antibiotics in gellan gum // 2609740
FIELD: medicine.SUBSTANCE: invention refers to a method for preparation of nanocapsules with aminoglycoside antibiotic selected from kanamycin, amikacin or gentamicin sulphate. The said method is characterized by application of gellan gum as a shell for the nanocapsules, wherein the aminoglycoside antibiotic is added by portions to a E472s containing gellan gum suspension in butanol at a aminoglycoside antibiotic:gellan gum weight ratio of 1:1 or 1:3, the mixture is stirred, methylene chloride is added and the resulting nanocapsule suspension is filtered, washed with methylene chloride and dried, the process takes 15 minutes.EFFECT: invention provides simplification and acceleration of the production process of the aminoglycoside antibiotic nanocapsules, as well as increase of their yield by weight.3 dwg, 7 ex

ethod for producing resveratrol nanocapsules in gellan gum // 2609739
FIELD: chemistry.SUBSTANCE: invention relates to a method for producing resveratrol nanocapsules. According to the invention resveratrol is added to the suspension of gellan gum in butanol in the presence of glycerol ester with one or two molecules of food grade a fatty acid and one or two molecules of citric acid under stirring at 1000 rev./min., followed by ethyl acetate. The resulting suspension of nanocapsules was filtered and dried at room temperature. The core : shell ratio in the nanocapsules was 3:1 or 1:5.EFFECT: quick and easy process of producing resveratrol nanocapsules and increase of mass yield.1 dwg, 3 ex

ethod of production of jujube nanocapsules in sodium alginate // 2609196
FIELD: nanotechnologies.SUBSTANCE: invention refers to the area of nanotechnologies, particularly to the method of production of nanocapsules, and describes the method of production of jujube nanocapsules. The method is characterized by the fact that jujube is used as a core and sodium alginate is used as a shell; during the method implementation, the powder from jujube berries is added to sodium alginate suspension in petroleum ether with the presence of E472c as a surface-active substance during agitation of 1,300 rpm, then, 5 ml of carbon tetrachloride as a precipitator is added, whereupon, the core/shell mass ratio is 1:1 or 1:3 on conversion to dry substance; the obtained suspension is filtered and dried at room temperature.EFFECT: method provides simplification and acceleration of the production process of nanocapsules, as well as reduction of losses during the production process.1 dwg, 3 ex
Production method for green tea extract nanocapsules in chitozan // 2609195
FIELD: food industry.SUBSTANCE: invention relates to the method of green tea extract nanocapsule production. The said method implies that green tea extract is added to the suspension of chitozan in petroleum-ether in the presence of glycerol ester with one-two molecules of fatty edible acids and one-two molecules of citric acid as surface active agent while mixing at 1300 rpm, afterwards acetone is added, the obtained nanocapsule suspension is filtered and dried at room temperature; herewith the mass ratio kernel/shell in nanocapsules accounts for 1:3, 1:1 or 1:5.EFFECT: invention provides for simplified and faster production of green tea extract nanocapsules, and for increase of their output by weight.2 dwg, 4 ex

ethod of producing nanocapsules of adenine in carrageenan // 2607654
FIELD: nanotechnology.SUBSTANCE: invention relates to a method of producing nanocapsules of adenine. Specified method is characterized by that carrageenan in benzene is added with glycerol ester with one or two molecules of edible fatty acids and one or two molecules of citric acid as a surfactant, the produced mixture is stirred, added with adenine powder, after formation of an independent solid phase is slowly added with petroleum ether, the produced suspension of nanocapsules is filtered, washed with petroleum ether and dried, herewith the ratio of nucleus/shell in the nanocapsules makes 1:3, 1:1 or 5:1.EFFECT: invention provides faster and easier process of nanoencapsulation of adenine, as well as higher mass output.1 cl, 1 dwg, 4 ex
 
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