(A61B5/0402)

ethod for prediction of long-term physical training efficiency in patients with hypertensive disease // 2642289
FIELD: medicine.SUBSTANCE: to predict the efficiency of long-term physical training in patients with essential hypertension, a test with measured physical activity is performed on a bicycle ergometer. The heart rate (HR) during rest, the threshold HR and HR recovery speed, as the difference between the threshold HR and HR at the end of a particular moment of recovery period. The rate of HR recovery is determined at the end of the 1st, 2nd and 5th minutes of the recovery period. The prognostic coefficients F1 and F2 are determined by the formulas F1=-62.4+1.16*x1+0.5*x2-0.09*x3+0.5*x4 and F2=-68.7+0.99*x1+0.78*x2-0.26*x3+0.7*x4, where x1 - HR during rest; x2 - rate of HR recovery at the end of the 5th minute of the recovery period; x3 - rate of HR recovery at the end of the 1st minute of the recovery period; x4 - rate of HR recovery at the end of the second minute of the recovery period. At F2 exceeding F1, efficiency of prolonged physical training is predicted.EFFECT: method increases the efficiency of physical rehabilitation of patients with essential hypertension, through objective selection of individual physical rehabilitation programs.2 ex, 2 tbl
ethod for prediction of compensatory arterial hypertension in patients with idiopathic hypotension combined with venous discirculation // 2641845
FIELD: medicine.SUBSTANCE: in patients of young age, cerebral hemodynamics, microcirculation and autonomic reactivity is examined by the following indicators: speed on straight sine (SS), fluxmotions index (FMI), percentages of low-frequency oscillations of tissue blood flow (%LF), percentages of high-frequency oscillations of tissue blood flow (%HF), ratio of sympatic and parasympatic influences in the normalized background recording units (LF/HF), as well as the duration of cephalgic syndrome and the presence or absence of eyelids and face edema in the morning are assessed. A prognostic coefficient (PC) is then evaluated: Then the sum of prognostic coefficients is calculated, dividing it by 38.1 and predicting the occurrence of arterial hypertension with the values from 1.6 to 2.34.EFFECT: method allows to predict the occurrence of compensatory arterial hypertension in young people with idiopathic arterial hypotension.1 tbl
ethod for selection of most effective antiarrhythmic drug for patients with extrasistoly // 2641164
FIELD: medicine.SUBSTANCE: patient with extrasystole receives anti-arrhythmic drugs to be tested one after the other. Each subsequent drug is administered after 3-5 half-lives of the previous one. Before and after the onset of the action of the antiarrhythmic drug studied, which is defined as the half-life of its half-life, an ECG study is performed. At that, linear deviation of corrected pre-ectopic interval separately for left and right sided ventricular extrasystole, supraventricular extrasystole not less than in 20 extrasystoles. Then the extrasystole index is calculated using the formula and with the maximum increase of the extrasystole index, compared to the baseline values, the studied antiarrhythmic drug is defined as the most effective.EFFECT: method provides a significant reduction in the time of drug selection in each case of extrasystole treatment.4 ex, 12 tbl
ethod for extracorporal shock-wave heart therapy in case of ischemic heart disease // 2638451
FIELD: medicine.SUBSTANCE: ECG with physical exertion is performed, and when ST segement depression of 1 mm and more and/or angina is detected, a three-week course of shock wave therapy is conducted. At that shock-wave therapy is performed in the mode of 100 pulses with energy density of 0.09 mJ/mm2 per 1 cm2 zone of each segment of the left ventricle. The exposure is provided 3 sessions per week, and on the first week during each of the three sessions, the exposure is exerted from the apical four-chamber position to the basal lower septal segment, basal anterolateral segment; from the apical two-chamber position to the basal lower segment, basal anterior segment; from the apical three-chamber position to the basal lower lateral segment, the basal anterior septal segment; on the second week - from the apical four-chamber position to the middle lower septal segment, middle anterolateral segment; from the apical two-chamber position to the middle lower segment, middle anterior segment; from the apical three-chamber position to the middle lower lateral segment, middle anterior septal segment; in the third week - from the apical four-chamber position to the apical septal segment, apical lateral segment; from the apical two-chamber position to the apical lower segment, the apical anterior segment; from the apical three-chamber position to the apical lateral segment, the apical septal segment.EFFECT: method allows to reduce the incidence of angina attacks, to increase tolerance to physical activity.2 ex
ethod for estimation of functional state of heart based on electrocardiogram analysis // 2635775
FIELD: medicine.SUBSTANCE: ECG recording is performed and heart rate and amplitude-time parameters of cardiac cycles are determined. Based on the actual R-R, Q-T and P-Q intervals for the actual heart rate, the hardware and software sequentially calculate the values of the proper Q-Tc and P-Qc intervals, the values of the actual P-Q and the proper P-Qc intervals are compared, and the deviation between their values is used to estimate the functional state of the AV connection. The value of the proper P-Qc interval is calculated by the original formula.EFFECT: initial stages of pathology are revealed.3 cl, 7 dwg, 4 ex
ethod for electrocardiogram processing to isolate stages in dynamics of changes in myocardium functional state // 2632756
FIELD: medicine.SUBSTANCE: patient's electrocardiogram signal is automatically recorded. It is digitized and recorded, cardiocycles are isolated, amplitudes and durations of the main signal deflection, segments and intervals. The coefficients of the continuous wavelet transform are calculated. At that, for each cardiocycle, its local points of extremum of surface zero isolines formed by the coefficients of wavelet transformation of the cardiac cycle under consideration are determined and indices of the characteristic cipher are assigned to them by indicating the letters corresponding to them above the horizontal line, if this point is maximum, and below the line if the point is minimum, their interrelationships are indicated by adding an index of the extremum point, if there is a relationship through a zero isoline between the extremum points and the lack of an index otherwise. Selection of the basic isolines and determination of the topological properties of their structure is carried out using the results of amplitude-time analysis of the cardiac cycle, transition from one electrocardiographic stage in the myocardium dynamics to another is established by changing the characteristic cipher of the cardiocycle with time when changes are recorded in the analyzed electrocardiogram.EFFECT: method allows to track the stages in the dynamics of changes in the functional state of the myocardium in an automatic mode.13 cl, 11 dwg

Radio channel system of cardiac monitoring, prevention and actions in critical situations // 2630126
FIELD: medicine.SUBSTANCE: system contains emergency medical service panels, each of which includes a microcontroller and associated database, a megahertz range modem and display, alert and control units, a patient control center including a server and associated data bank, an automated workstation of the center administrator and a modem of the megahertz range, as well as wearable distant-reading instruments, each of which contains a multichannel microcontroller, to which the microprocessor with a keyboard, a ECG measurement unit, a respiration analysis unit, a haemodynamics monitoring unit and megahertz range modem, as well as the patient mobility measuring instrument are connected, the output of the patient mobility measuring instrument is connected to the corresponding multichannel microcontroller input, to the outputs of which an audio notification unit and a display are connected. Each wearable distant-reading instrument includes a GPS/GLONASS module, a battery power control and monitoring unit, and a gigahertz range modem, such as a WiFi modem. Moreover, all the above-mentioned modems of the megahertz range are made in the form of low-power "short-range devices" using unlicensed frequency bands, such as 433 or 868 MHz.EFFECT: increased efficiency of the system by eliminating traffic overload.4 dwg

Electrical activity map provision system // 2622371
FIELD: medicine.SUBSTANCE: system to provide a heart electrical activity map for a living being comprises: projection images provision unit, surface electrodes position determination unit, heart structure determination unit, electrical activity map determination unit to determine the electrical activity maps for the heart structure. The method is implemented through the system.EFFECT: reduced studies trauma due to non-invasiveness, improved quality of heart electrical activity maps creation.10 cl, 3 dwg
ethod of diagnosing critical fetus condition // 2620005
FIELD: medicine.SUBSTANCE: remote cardio-feto monitoring is carried out for 10-30 minutes using fetus doppler in pregnant women, starting from 26 weeks, in the sitting position. Fetal heart rate, posteriori entropy of the fetal heart rate and short-term heart rate variability (STV) are determined according to Redman. Fetus condition coefficient P is calculated based on the resulting data according to the formula. If values of fetus condition coefficient P are less than 500, the critical fetus condition is diagnosed.EFFECT: method enables to improve the accuracy and reliability of the diagnosis.3 ex

ethod for bladder fullness diagnosis // 2619752
FIELD: medicine.SUBSTANCE: electrodes are applied to the skin in the bladder location area. They are connected to a bioelectric potentials amplifier to obtain two leads which measure bioelectrical activity signals of the bladder walls. Electrocardiograms are recorded simultaneously for signal filtering. The received signals are mathematically processed by normalizing and plotting of bladder and electrocardiogram signals spectra by the Fourier method. The bladder signal is filtered from the electrocardiogram signal by bladder signal spectrum division by the electrocardiogram signal spectrum. Characteristic spectra frequencies are selected from the most active range of 0.7 Hz, 1.5 Hz, 1.7 Hz. The said measurement is performed twice - before and after a water-drinking stress. The characteristic frequencies amplitudes are compared, and bladder fullness is judged by the degree of their increase.EFFECT: method allows accurate, simple and non-invasive determination of bladder fullness due to the simultaneous recording of bladder wall bioelectrical activity and electrocardiogram signal, followed by bladder signal filtration from the electrocardiogram signal.3 dwg

Device for cardiographic monitoring of patients state // 2615721
FIELD: medicine.SUBSTANCE: device for cardiographic monitoring of patients comprises a display, an interface, ECG electrodes to obtain ECG signals from the patient's body, with the output connected to the primary signal processing input, the other input of this unit is connected to the time sampling unit output, and the primary signal processing unit output is connected to the channel switching unit. The channel switching unit outputs are connected to the discrete Fourier transformation unit, with the output containing amplitude, frequency and harmonic phase values of the test signal, and to the patient data input unit. Harmonics are processed in the cardiogram retainer which stores and outputs the test signal harmonic amplitudes within the required amount of time. The harmonic amplitudes enter the ECG image determining unit, which compares the image obtained from the ECG electrode with due regard to confidence intervals and a certain degree of reliability to the images from the cardiogram images database. The determinating unit output is connected to the states fixation and dynamics analysis unit input, where, according to the cardiogram imagess of all ECG electrodes, a diagnosis is formed by comparing a set of cardiogram images from ECG electrodes to a set characterizing the disease diagnosis from the cardiac diagnoses base with due regard to confidence intervals and a certain degree of reliability. The same unit determines the degree of diagnosis reliability and the diagnosis dynamics, depending on the previous study of this patient and the diagnosis time. The data are displayed, transferred to the interface for storage and research on other technical means and to the patient data input unit, where they are stored in the respective patient archives.EFFECT: improved accuracy of cardiac status assessment and better definition of particular disease parameters, increased speed of diagnosis.3 cl, 14 dwg

Noninvasive method for electrophysiological heart characteristics determination // 2615286
FIELD: medicine.SUBSTANCE: based on the known detailed models, a stochastic model of the epicardium repolarization current is developed, and its parameters are determined based on epicardial potential values samples found in the solution of the inverse electrocardiographic task in the reference points of the patient's heart computer model.EFFECT: method allows to extend the functionality of electrocardiographic examination, to determine the ion currents components based on the epicardium potential values in the reference points of the patient's heart computer model.26 dwg

ethod for quantitative estimation of daily heart rate variability // 2614886
FIELD: medicine.SUBSTANCE: heart rate variability (HRV) analysis is performed over the long periods of time for healthy subjects and patients with various forms of cardiopathology. It involves 24-hour ECG monitoring. Rhythmogram is plotted for the entire period of observation. The following is allocated on the rhythmogram: all double breaks - four consecutive intervals RR-RR[i], RR[i+1], RR[i+2], RR[i+3], where the adjacent RR intervals differ by at least 24 ms and for which the group of inequalities RR[i]<RR[i+1]>RR[i+2]<RR[i+3] or the group of inequalities RR[i]>RR[i+1]<RR[i+2]>RR[i+3] is made. Rhythmogram is divided into short sections of 33 RR intervals, for each the average value of RRM and rhythmogram short sections variations (SSV) are determined. All short rhythmogram sections are divided into sections containing double rhythmogram breaks and areas not containing any double breaks. Change Gap for RRM values measured in seconds, is divided into 8 ranges arranged in the ascending order with numbers i, where i = 1, 2, 8: (1) <0.573, (2) 0.573-0.648, (3) 0.649-0.724, (4) 0.725-0.800, (5) 0.801-0.873, (6) 0.874-0.948, (7) 0.949-1.024, (8)>1.024. Each short rhythmogram section belongs to the group with the number equal to the band number, covering its RRM value. For each group obtained by this method and having number i, number n1(i) of short rhythmogram sections covered by the i-th group and not containing double breaks, mean SSVM1(i) value, SSV values of sections belonging to the i-th group and not containing double breaks, number n2(i) of short rhythmogram sections covered by the i-th group and containing double breaks, mean SSVM2(i) value,SSV values of sections belonging to the i-th group and containing double breaks. The weighted average rhythmogram variations WARV1 and WARV2 are calculated by the formula: WARV1 = Σ (nl(i)*q(i)*SSVM1(i))/(n1(l)+n1(2)+…+ n1(8)), WARV2 = Σ (n2(i)*q(i)*SSVM2(i))/(n2(1)+n2(2)+…+n2(8)). In the formulas: i = 1,…,8 are the numbers of ranges, and the weighting factors q(i) are given by q(1) = 3.04, q(2) = 2.75, q(3) = 2.33, q(4) = 1.88, q(5) = 1.56, q(6) = 1.34, q(7) = 1.15 and q(8) = 1. Double breaks effect factor is calculated DBEF = WARV2/WARV1. If WARV1<550 ms, or DBEF>3, or DBEF>2 at WARV1<700 ms, HRV is considered abnormal.EFFECT: method allows to quantify the daily heart rate variability to determine objectively whether the heart rate variability is normal.1 dwg, 2 tbl
Differential diagnostic technique for cardiogenic myocardial ischemia and spinal-cardial inhibitory reflex // 2602952
FIELD: medicine.SUBSTANCE: invention relates to medicine, to cardiology. At first on background of pain syndrome, specific for myocardial ischemia and ischemia of upper part of back, ECG is recorded. Then double-sided paravertebral block is made with anaesthetic solution in amount of 5.0-10.0 ml in each injection at level of VII cervical and I, II, III, IV and V thoracic vertebrae. Then after 30-45 min ECG is recorded again and obtained record is compared to ECG record, made before block. At positive dynamics in ECG results, ischemia is diagnosed, caused by spinal-cardial inhibitory reflex. In absence of positive dynamics cardiogenic myocardial ischemia is diagnosed.EFFECT: method increases efficiency of differential diagnostics of cardiogenic myocardial ischemia and spinal-cardial inhibitory reflex, accompanied by pain syndrome, specific for myocardial ischemia and ischemia of upper thoracic spine.1 cl, 1 ex
ethod for assessing effectiveness of ventricular contractions frequency in patients with constant atrial fibrillation // 2600489
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiology. Analysis of parameters of ECG Holter monitoring. Calculation is performed of average frequency of ventricular contractions on background of atrial fibrillation every hour of examination in day (from 6 to 22 hours) and night (from 22 to 6 hours). They are compared with presented range of target values: in daytime 60-100 contractions per minute, at night 50-80 contractions per minute. Then calculation of duration of time of ventricular contractions being in set range is performed. Patients with atrial fibrillation are separated according to efficiency into two groups: with efficient 50 % and more time of day or ineffective-less than 50% of time of day-frequency control contractions.EFFECT: method enables evaluation of efficiency of daily monitoring VCF in patients with constant AF for a day with underlying conducted treatment, if necessary, corrected therapy scheme.1 cl, 2 ex

ethod for monitoring of patient cardiac activity // 2593351
FIELD: medicine. SUBSTANCE: invention relates to medicine, specifically, to diagnosis and monitoring of ECG and pulse frequency of a patient. Patient's cardiac activity is monitored. For this purpose, method includes using, located in functional connection, a recording system, consisting of a pulse sensor comprising a pulse wave sensor, first short range radio transmitter, ECG sensor comprising an ECS sensor, sensor of patient's physical activity, as well as second short range radio transmitter, data collection and processing system, including third short range radio transmitter, long-range radio transmitter, performing pickup, analogue-to-digital conversion and accumulation of the patient's physiological signals. Method incudes additionally accumulating patient's physiological signals over a fixed period of time. For every next fixed time interval, parameters of patient's physiological signals accumulated during previous fixed time interval are determined. Method includes identification of obtained pulse rate of patient Pf to interval of permissible values of patient's pulse RP. Detecting distorted areas of ECS of patient. Determining coefficient Pd of ECS distortions of patient. Storing undistorted areas of ECS of patient obtained over fixed time interval. Comparing signal level of patient's physical activity sensor with setting W of level of patient's physical activity. If patient's pulse rate Pf belongs to range of permissible values of patient's pulse rate Rp, coefficient Pd of distortions of ECS of patient does not exceed maximum coefficient of distortion of ECS of patient RG, patient's pulse rate Pf and parameters of ECS of patient are transmitted to operational observation station and obtained data are stored. When patient's pulse rate Pf belongs to interval of permissible values of patient's pulse RP, for coefficient Pd of distortions of ECS of patient exceeding maximum value of distortion of ECS of patient RG, patient's pulse rate Pf is transmitted to operational observation station, message is sent to patient to check attachment ECG sensors and obtained data are stored. When patient's pulse rate Pf is outside interval of permissible values of patient's pulse rate RP, coefficient Pd of distortions of ECS of patient less than maximum value of distortion coefficient RG of ECS of patient, transmitting parameters of ECS of patient of operational observation stations, message is sent to a patient on need to check connection pulse sensor and obtained data are stored. When patient's pulse rate Pf is outside interval of permissible values of patient's pulse rate RP, coefficient Pd of distortions of ECS of patient exceeding maximum value of distortion coefficient RG of ECS of patient, signal level of sensor of patient's physical activity exceeding setting W of patient's physical activity level message is sent to patient to check attachment ECG sensors and sensor of pulse and obtained data are stored. At level of signal from sensor of patient's physical activity, not exceeding setting W of patient's physical activity level, patient is sent messages on critical state, signal is transmitted warning about critical state of patient, accompanied by data on patient's pulse and parameters of ECS of patient for operational observation station of data and obtained data are stored. EFFECT: method improves accuracy of obtained data of monitoring patient's cardiac activity and speed of investigation, enabling patient's notification on loss or deterioration of contact of recording sensors with patient's body. 7 cl, 3 dwg

ethod for prediction of atrioventricular block of i, ii and iii degree // 2591839
FIELD: medicine.SUBSTANCE: invention relates to medicine, specifically to cardiovascular diagnosis. Excitation propagation model parameters are determined in myocardium. On basis of obtained model, analysing entropy of simulating excitation propagation in myocardium by selecting variables of components of excitation propagation simulation results in myocardium. Formation of two-dimensional information-measuring quantum entropy evaluation, comparing quantisation results of simulation and determining entropy of distribution of information-measuring quanta. Then myocardial recovery curve shape is selected by establishing conformity of entropy of distribution of information-measuring quanta and entropy of distribution of parameter of a patient's heart recovery curve shape. Then performing analysis of refractivity of myocardium by determining beginning of development degree III atrioventricular block at the point of maximum heart rate dependence. Determining beginning of development of "advanced" II degree of atrioventricular block with falling out of half of pulses in flex point of dependence of heart rate at fall out of half of pulses. Determining beginning of II degree of atrioventricular block at point of maximum rate of change of dependence of heart rate. Determining beginning of development of I degree atrioventricular block in flex point of change of dependence of heart rate.EFFECT: method allows quick evaluation of possible states of cardiovascular system.1 cl, 9 dwg

ethod for diagnosis of vegetative dystonia syndrome on hypotonic type // 2587036
FIELD: medicine.SUBSTANCE: method includes analysing 4 highly informative value of heart rate variability and heart rate in background sample HR<69 beats/min; heart rate in orthostatic sample HR < 88 beats/min; balance of sympathetic and parasympathetic effects LF/HF < 0.58 - WDS, background test, balance of sympathetic and parasympathetic effects LF/HF < 3.40 - WDS, orthostatic test, vegetative dystonia syndrome is diagnosed hypotonic.EFFECT: method enables accurate prediction of hypotonic vegetative dystonia due to high specificity and sensitivity of a series of heart rate variability parameters.1 cl, 2 ex, 2 tbl

ethod for early diagnosis of autonomic cardiac neuropathy in patients with arterial hypertension and metabolic disorders // 2585741
FIELD: medicine.SUBSTANCE: method comprises performing background examination of cardiac rhythm variability in a prone position 5 minutes and when performing active orthostatic test for 5 minutes with subsequent spectral analysis and calculation of relative spectral values. Method includes calculating ratio of indices %LFortho-test/%LFbackground and %VLFortho-test/%VLFbackground during orthostatic test to such background record. If ratio %LFortho-test/%LFbackground is less than 1.0 in combination with ratio %VLFortho-test/%VLFbackground is more than 1.0 cardial autonomous neuropathy is diagnosed before onset of clinical symptoms.EFFECT: method allows early, before clinical manifestations, detection of cardial autonomous neuropathy, which will allow prescribing adequate pathogenetic therapy.1 cl, 2 tbl, 1 dwg, 2 ex

odified method for point selection for chest leads recording // 2583719
FIELD: medicine.SUBSTANCE: ECG electrodes are placed on the skin of a patient's left pectoral region in the following points: point 1 - an electrode which is normally attached to a right hand, is placed in the 2nd intercostal space along a left parasternal line; point 2 - an electrode which is normally attached to a left hand, is placed in the middle of a left deltopectoral groove. Point 3 is localised by means of a formula taking into account the patient's anatomy. An electrode which is normally attached to a left leg, is placed into point 3. And 6 approximated leads are recorded: Ia is a bipolar recording from point 1 to point 2; IIa is a bipolar recording from point 2 to point 3; IIIa is a bipolar recording from point 3 to point 1; aVRa is a unipolar enhanced recording from point 1; aVLa is a unipolar enhanced recording from point 2; aVFa is a unipolar enhanced recording from point 3.EFFECT: method makes it possible to provide higher information value and quality of ECG recording, diagnose arrhythmias, and monitor ischemic changes in different myocardial segments.5 dwg, 3 ex

ethod for enhanced external counterpulsation // 2580977
FIELD: medicine.SUBSTANCE: method involves providing enhanced external counterpulsation. ECG pulses are passed through a frequency divider twice or more times, whereas the signal of the output of the frequency divider is used to synchronise the cycles of inflation and deflation of compression cuffs, which generate periodic pressure pulses on tissues of the patient's lower extremities and small pelvis.EFFECT: method makes the procedure of enhanced external counterpulsation more comfortable and increases the wear resistance of the used equipment.3 dwg

ethod for generating informative high-stability electrocardiogram independent of angulation of cardiac electrical axis // 2580976
FIELD: medicine.SUBSTANCE: generating EEG E-vector amplitude requires passing each of the uI, uII, uIII signals in the leads I, II, III through square-law generators. The signals derived at the outputs of the square-law generators are summed up, and the produced value is used as an output signal.EFFECT: method ensures increasing the accuracy of each cardiac cycle, providing the more reliable separation of R-wave of EEG, and producing more stable and noise-resistant EEG.4 dwg

ethod for analysing disturbed haemodynamic regulation // 2578367
FIELD: medicine.SUBSTANCE: electric-cardio signal and central rheogram are recorded with conducting functional exercise test. Cardiac cycle lengths are isolated from the EEG signal, whereas a systolic volume and total peripheral resistance are isolated from the rheogram. The test load represents an active orthoclinostatic test. Each testing phase involves recording from two hundred to four hundred cardiac cycles; in addition to the initial time sequences of the cardiac cycle lengths, systolic volume and total peripheral resistance in each cardiac cycle, the standard time sequences are also analysed. The sequences consist of logarithms of relative variations of the initial values derived by taking the logarithms of a current value of each parameter recorded as related to the previous one. That is followed by using the statistic parameters of the initial and standard time sequences for the automated assignment of the examined patient to one of the known groups.EFFECT: invention enables to provide the higher information value of the method for analysing the disturbed haemodynamic regulation, as well as ensures the differential diagnosis of cardiovascular pathologies.9 cl, 4 dwg, 11 tbl

ethod for selecting approximated lead points // 2571709
FIELD: medicine.SUBSTANCE: ECG electrodes are placed on the skin of a patient's left pectoral area in certain points. Point 1 - a standard ECG electrode attached to a right arm is placed in the 2nd intercostals space along a left parasternal line. Point 2 - a standard ECG electrode attached to a left arm is placed in the middle of a left deltoid pectoral sulcus. Point 3 is localised by means of an original formula taking into account the anatomical parameters of the patient's chest. A standard ECG electrode attached to a left leg is placed into point 3. Herewith, 6 approximated ECG leads are recorded: Ia is a bipolar record from point 1 to point 2, IIa is a bipolar record from point 2 to point 3, IIIa is a bipolar record from point 3 to point 1, aVRa is a unipolar augmented record from point 1, aVLa is a unipolar augmented record from point 2, aVFa is a unipolar augmented record from point 3.EFFECT: method enables increasing the information value and quality of ECG recording, diagnosing rhythm disturbances, monitoring ischemic changes in various myocardial segments.5 dwg, 3 ex

ethod for adaptive filtration of electric cardiosignal // 2568817
FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly cardiology, and may be used for adaptive noise suppression in an electric cardiosignal (ECS). Implementing the method for adaptive filtration of an electric cardiosignal involves picking up a segment equal to TP segment of the ECS in each cardiac cycle from an additive mix of the ECS and noise and choosing the noise at this ECS segment and forming a noise-free ECS. After the segment equal to the TP segment of the ECS is picked out, a segment equal to PQRST complex of the ECS is selected. After the noise is selected in the segment equal to the TP segment of the ECS, a noise type is determined; a filter is selected, and the selected ECS segments are filtered in accordance with the determined noise type.EFFECT: using the invention enables increasing a quantity of types of the suppressed noise in the ECS.5 dwg
ethod for prevention of recurrent atrial fibrillation following cardiosurgical operations // 2567920
FIELD: medicine.SUBSTANCE: preoperative stage involves using amiodarone 0.6-1.2 g/day with ECG and heart rate monitoring to achieve a total dose of 9.6-10.2 g. If QT interval is no more than 500 msec with the absence of cardiac conduction disease and bradycardia events, a maximum dose of the preparation is administered. If observing cardiac conduction disease and bradycardia events following an initial daily dose, a dosage is supposed to decrease daily by 0.2 g/day, but not less than 0.6 g/day to achieve normal ECG. A principal stage of the operation is combined with radiofrequency ablation of pulmonary venous entries and auricles. Besides, two electrodes are intraoperatively anchored to a right auricle and a right ventricle and attached to an external pacemaker. Starting from the intraoperative period and further, a bipolar dual electric cardiac stimulation is performed with a heart rate 10 beats/min as much as a proper rhythm with proper rhythm monitoring for 7-10 days. After the operation, intravenous amiodarone administration continues in a dose of 0.4 g/day on the operative day, in a dose of 0.2-0.4 g/day on the second postoperative day. Further, amiodarone is administered in the tabletted form orally in a dose of 0.2 g/day for 6 months with ECG monitoring. The preparation is withdrawn with persistent sinus rhythm and the absence of paroxysmal events of atrial fibrillation.EFFECT: more effective prevention of recurrent atrial fibrillation by optimising the combination anti-arrhythmic medication and electric stimulation therapy.2 ex

ethod of express-estimation of electric heart stability // 2567271
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiology. Electrocardiosignal registration is carried out. The electrocardiosignal is loaded into a mobile computer device. After that, preliminarily processing of the electrocardiosignal is carried out by its decomposition into a set of frequency components and a residue. Nonlinear threshold processing of the frequency components is carried out, the residue and the frequency components, which have passed the procedure of nonlinear threshold processing, are summed up and on this basis the express-estimation of the electric stability of the heart is realised. In case if a dangerous for life pathology is determined, ambulance is called to the patient's location with sending to the patient a message "Wait for ambulance".EFFECT: method makes it possible to determine the electric stability of the heart under conditions of the patient's free motor activity and in case of necessity render qualified medical aid.9 dwg
ethod for prediction of natural clinical course of short pq interval phenomenon // 2560776
FIELD: medicine.SUBSTANCE: overdriving transoesophageal atrial pacing is combined with electrocardiogram recording. The sinus rhythm PQ interval size and maximum and minimum St-R interval sizes are determined during the overdriving transoesophageal atrial pacing. If the PQ interval size is not less than 110 ms, the min St-R interval size is more than 108 ms, and the max St-R interval size is more than 127 ms, the PQ interval normalisation is predicted. If the PQ interval size is less than 110 ms, the min St-R interval size is less than 108 ms, and the max St-R interval size is less than 127 ms, the preserving short PQ interval is predicted.EFFECT: method enables predicting the natural clinical course of the short PQ interval phenomenon in children and adolescents with using the non-invasive ECG diagnostics of the atrioventricular conduction parameters.2 ex

Diagnostic technique for vegetative insufficiency // 2559578
FIELD: medicine.SUBSTANCE: cardiac rhythm is recorded, processed by fast Fourier transformation followed by wave picking within the frequency ranges: VLF within the range of 0.004-0.08 Hz, normal wave amplitude 30-150 ms2/Hz, LF within the range of 0.09-0.16 Hz, normal wave amplitude 15-25 ms2/Hz, HF within the range of 0.17-0.5 Hz, normal wave amplitude 15-35 ms2/Hz. A heart rate variability (HRV) is examined while the patient performs an active orthostatic test. The patient initially lies in a horizontal position, and then goes into a vertical position and into a horizontal position again. If the LF and HF amplitude decreases after the patient goes into the vertical position, by more than 50% of the initial horizontal values, vegetative insufficiency is diagnosed. If the LF and HF amplitude decreases after the patient goes into the vertical position, by more than 50% of the initial horizontal values, and the VLF amplitude decreases after the patient goes into the vertical position, by more than 50% of the initial horizontal values, vegetative insufficiency with depressed compensation abilities of hemodynamic regulation is diagnosed.EFFECT: technique enables detecting the specific pathophysiological mechanisms of disturbed vegetative and neurohumoral regulation of cardiac activity by evaluating the spectral indices when performing the orthostatic test.2 ex, 2 tbl

ethod for assessing cardiovascular response to physical load // 2558973
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to the cardiologic research. A patient's rest electrocardiogram is recorded. The patient's post-load electrocardiogram is recorded. The R-R interval lengths are compared thereafter. The Q-P and T-Q interval lengths are measured on both the electrocardiograms. The number of rhythm waves having a peak within the range of 0.05 to 0.1 seconds is measured on the formed cardiointervalograms; the number of cardiac cycles making such a rhythm wave is determined. A moment whereat the first rhythm wave having a peak of 0.05 to 0.1 seconds starts is found on the first cardiointervalogram; recording this moment enables assessing the functional state of the atrium and ventricle.EFFECT: method enables assessing the functional state of the atrium and ventricles separately by analysing both the rest and post-load electric systole and diastole lengths separately.3 cl, 12 dwg, 3 ex
ethod for rehabilitation of patietns with ischemic heart disease // 2556485
FIELD: medicine.SUBSTANCE: stress test is administered by performing a physical load accompanied by recording cardiac parameters followed by performing a training load. The training load is preceded by administering a repeated stress test 30-60 minutes following the first one. The cardiac parameter consists in recording ST segment displacement and calculating ST index. The ST indices subsequent to the results of the first and second stress tests are compared. If the second index tends to decrease as compared to the first one by at least 10%, the training load is performed. A third stress test is administered 30-60 minutes later to evaluate a third ST index. The training load is performed for 24-48 hours on completion of the second stress test. The training load represents alternative clamping and blood flow recovery in the peripheral vessels. One cycle is expected to consist of at least 4 cycles of clamping and recovery procedures in the peripheral blood vessels. Besides, each clamping and recovery within the training load cycle alternates for 3-5 minutes.EFFECT: method enables reducing the rehabilitation time of the IHD patients and reducing a risk of complications by providing a sparing load pattern.2 cl

Electrocardiograph for non-invasive real-time micropotential recording on electrocardiogram // 2552876
FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely to devices for measuring bioelectric potentials of the heart. An electrocardiograph comprises a supply unit, electrodes, a microcontroller, a computer, an analogue-to-digital converter, and a digital-to-analogue converter. The electrocardiograph has a multi-channel structure and comprises several identical channels. The electrodes are medical nanoelectrodes for the chest EEG recording. Outputs of the nanoelectrodes are connected to inputs of measuring amplifiers; outputs of the measuring amplifiers are connected to the first inputs of operational amplifiers outputs of which are connected to inputs of the analogue-to-digital converter; outputs of the analogue-to-digital converter are connected to inputs of microcontrollers, outputs of which are connected to the computer and to the second inputs of the operational amplifiers through the digital-to-analogue converter.EFFECT: invention aims at the higher resolution of electrocardiographic equipment for non-invasive real-time micropotential recording on the electrocardiogram without applying any analogue and program filters, collecting cardiac pulses which lead to the distortion of true bioelectric activity of the heart for the purpose of early diagnostic of the heart diseases and eliminating the episodes of sudden cardiac death.20 dwg

ethod for optimising atrioventricular delay in patients with cardiac resynchronising therapy // 2551636
FIELD: medicine.SUBSTANCE: continuous monitoring and ECG recording are performed. The ECG findings are used to specify a delay in shape of R wave and a length of an antrioventricular interval. The final result of atrioventricular delay is a symmetrical crowned P wave.EFFECT: method provides increasing the effectiveness of cardiac resynchronising therapy by reducing complications and improving the patient's quality of life.1 tbl, 1 ex, 1 dwg
Differential diagnostic technique for cardiogenic myocardial ischemia and genital-cardial inhibitory reflex // 2550000
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to cardiology and gynaecology, and can be used in the differential diagnostics of cardiogenic myocardial ischemia and the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology. That is ensured by ECG recording. That is followed by two-side block of round ligaments of the uterus by an anaesthetic solution in an amount of 15.0-20.0 ml from each side. The ECG is recorded again 60-90 min after the block, and the recording is compared to the pre-block ECG. If the ECG findings tend to be positive, ischemia caused by the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology is diagnosed. If no positive dynamic is observed, cardiogenic myocardial ischemia is diagnosed.EFFECT: technique provides the effective differential diagnosis of cardiogenic myocardial ischemia and the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology.1 ex
ethod of predicting development of acute foetus hypoxia in labour // 2547256
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to obstetrics and gynaecology. After anamnesis analysis, the presence of the foetoplacental failure of a compensated form, oligohydramnios are identified. The day before labour cardiotocographic (CTG) examination is carried out, its results are evaluated, and the index STV is determined. Foetal monitoring is carried out, during which the sum of areas of decelerates in the active phase of I period of labour is determined with the external CTG and STV index with direct CTG after 1 hour of monitoring. The obtained data are processed with the calculation of a prognostic index. On the basis of the obtained index value the development of acute foetus hypoxia is predicted.EFFECT: method makes it possible to predict the development of acute foetus hypoxia in labour, which makes it possible to determine further obstetric tactics of labour management in due time.2 ex

ethod for preventing anthracycline cardiotoxicity in patients with breast cancer // 2546399
FIELD: medicine.SUBSTANCE: in the patients diagnosed with breast cancer and recommended to have a chemotherapeutic course, the heart rate is measured one week before the treatment according to electrocardiography after a 5-minute rest. If the measured heart rate is 70 beats per minute or more, ivabradine is prescribed in a daily dose of 10 mg. Electrocardiography is repeated after a 5-minute rest 4 weeks later. If the measured heart rate is 70 beats per minute or more, the dose is titration is made to 15 mg a day. If the measured follow-up heart rate is less than 70 beats per minute, the daily dose is kept at 10 mg. If the initial heart rate is less than 70 beats per minute, trimetasidine is prescribed in a daily dose of 70 mg for the whole period of treatment independent from the further heart rate measurement. All the patients take the preparation throughout the duration of 6 months.EFFECT: method enables reducing the cardiotoxic action of the anthracycline chemopreparations in the patients with breast cancer.3 ex, 4 dwg

ethod for prediction risk of cardiovascular complications following ischemic stroke // 2545437
FIELD: medicine.SUBSTANCE: Holter ECG monitoring with recording total vegetative activity and measuring heart rate variability is conducted on the 21st day following ischemic stroke. Daily standard deviation of NN intervals (SDNN) is determined. If SDNN<71 ms, a high risk of cardiovascular complications following ischemic stroke is predicted.EFFECT: method enables providing the informative and most accurate possible prediction of the risk of cardiovascular complications following ischemic stroke on the ground of daily standard deviation of NN intervals, which represent an independent predictive factor.3 ex, 1 dwg, 2 tbl
ethod for predicting risk of cerebral complications following ischemic stroke // 2545435
FIELD: medicine.SUBSTANCE: on the 21st day following an acute ischemic stroke, the patient has continuous Holter monitoring and ventricular extra systole recording. Observing frequent single ventricular extra systoles in number of more than ten an hour and grouped ventricular extra systoles enables predicting the high risk of cerebral complications following the ischemic stroke.EFFECT: method enables predicting the high-grade risk of cerebral complications on the basis of ventricular extra systoles, which are an independent predictive factor of recurrent cerebral complications.3 ex, 3 tbl

ethod of predicting risk of cardiac complications after ischemic stroke // 2545430
FIELD: medicine.SUBSTANCE: estimation of the heart rate variability is realised by a method of 24-hour Holter monitoring of the 21st day from the moment of ischemic stroke development. After that, the power of a low-frequency spectrum is determined by means of spectral analysis and, if its value is lower than 117 ms2, a high risk of cardiac complications after the ischemic stroke is predicted.EFFECT: method makes it possible to increase the accuracy of predicting a risk of development of cardiac complications after the ischemic stroke due to the identification of a certain LF value, an independent prognostic factor.2 ex, 4 tbl, 2 dwg
Differential diagnostic technique for cardiogenic mypcardial ischemia and ileocecal-cardial inhibitory reflex // 2541826
FIELD: medicine.SUBSTANCE: ECG is recorded. That is followed by a needle block of an ileocecal plexus with an anaesthetic solution in an amount of 60.0-80.0 ml; that is followed by recording another ECG after 60-90 min. The record is compared to the pre-block ECG record. If observing a positive dynamics in ECG results, ischemia caused by ileocecal-cardial inhibitory reflex is diagnosed, while no positive dynamics shows cardiogenic myocardial ischemia.EFFECT: providing the more effective differential diagnostics of cardiogenic myocardial ischemia and ileocecal-cardial inhibitory reflex with underlying ileocecal patency.1 ex
ethod for prediction of risk of cardiovascular complications following ischemic stroke // 2541335
FIELD: medicine.SUBSTANCE: heart rate variability is assessed. The assessment procedure involves 24-hour Holter monitoring on the 21st day from the moment of the ischemic stroke occurred. And if observing brady-arrhythmias presented by degree 2-3 atrio-ventricular block or degree 2-3 sinoatrial block and sinus pauses of more than 2 sec long, a high risk of cardiovascular fatal complications following the ischemic stroke is predicted.EFFECT: method provides the high informative and flexible prediction of the risk of cardiovascular fatal complications following the ischemic stroke in the patients with cerebrovascular, cardiac, endocrine comorbidities.3 tbl, 3 ex

Electric cardiosignal recorder in free motion activity // 2540528
FIELD: medicine.SUBSTANCE: electric cardio signal recorder in free motion activity comprises an amplifier (1), an analogue-to-digital converter with a multiplex switch (2) and series decomposition unit (3), second arithmetical-logical unit (4), an arithmetic unit (5), an increment code analyser (6), a switchover unit (7) and a digital modem (8), as well as a control unit (9), first (12) and second (10) memory units, an increment code counter (11). A second output of the second arithmetical-logical unit (4) is connected to a first input of a decomposition unit (3); an output of the second memory unit (10) is connected to a second output of the second arithmetical-logical unit (4); a second output of the increment code analyser (6) is connected to a first input of the first memory unit (12), while a third output - to a first input of the increment code counter (11), an output of which is connected to a second input of the first memory unit (12) an output of which us connected to an second input of the switchover unit (7); first, second, third, fourth, fifth and sixth outputs of the control unit (9) are connected respectively to a first input of the analogue-to-digital converter with the multiplex switch (2), a second input of the decomposition unit (3), an input of the second memory unit (10), a third input of the second arithmetical-logical unit (4), a second input of the increment code counter (11) and a third input of the switchover unit (7). The device also comprises an electrode break detector (13) and a heart critical state detector (14). The amplifier (1), the electrode break detector (13), the analogue-to-digital converter with the multiplex switch (2), the heart critical state detector (14) and the decomposition unit (3) are series connected. A seventh output of the control unit (9) is connected to a fourth input of the switchover unit (7); a second output (17) of the electrode break detector (13) is connected to a first input of the control unit (9), a second input of which is connected to a second output (24) of the heart critical state detector (14), and a second output of the second memory unit (10) is connected to a second input (22) of the heart critical state detector (14).EFFECT: using the invention enables enhancement by detecting the electrode break and the heart critical state in free motion activity.3 cl, 12 dwg
ethod of complex evaluation of indications for administration of cardiometabolic therapy in case of infectious diseases // 2539990
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to paediatric cardiology and paediatric infectious diseases, and can be used for evaluation of indications for cardiometabolic therapy in case of infectious affection of myocardium in children. For this purpose quantitative evaluation of clinical, electrocardiographic, biochemical and echocardiographic indices is determined and realised. As clinical indices auscultative symptomatic: sonority of tones, presence of noises, parameters of arterial pressure are evaluated. As biochemical indices evaluated are: activity of cardiospeciphic enzymes: MB-fraction of creatine phosphokinase, α-hydroxybutyrate dehydrogenase, aspartic transaminase, alanine transaminase and cardiospecific troponin I protein. Echocardiographic examination is realised with application of Dopplerography for evaluation of diastolic ventricular function. Each of indices is evaluated by from 1 to 3 points. Points are summed up and obtained result is used to evaluate indications for cardiometabolic therapy. If the total sum is lower than 3 points, cardiometabolic therapy is not indicated. If the total sum is from 3 points to 7 point including, peroral introduction of cardiometabolic preparations is carried out. If the total sum is from 8 points and higher, parenteral introduction of cardiometabolic preparations is realised.EFFECT: method provides possibility of determining presence of indications to administering cardiometabolic therapy objectively in minimal terms, including situations, when part of results of additional examination is absent because of some reasons, and of evaluating its efficiency in differential way.1 tbl, 4 ex

Early diagnostic technique for cardiovascular diseases by multichannel spectral analysis of slow waves of heart signals // 2537771
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to non-invasive techniques for qualitative-quantitative analysis of the cardiovascular functional state. A pulse signal and an electric heart signal are recorded for 2-3 minutes. The slow waves are recovered from two heart signals; slow-wave spectra are detected in two channels. The windowed Fourier transform is used to calculate spectral ratio powers of the slow waves of the heart signal in the second-order slow-term within the range of 0.01 to 0.05 Hz, in the first-order slow-term within the range of 0.05 to 0.15 Hz, in the respiratory component within the range of 0.15 to 0.5 Hz. The derived data are used to form six informative criteria X…X6. As the heart signal recorded in one of the channels, a heart rate is calculated and used as the seventh informative criterion. The generated seven-element vector of the informative criteria is supplied to an input of a trained neuron network, outputs of which correspond to the allocated classes of the cardiovascular diseases.EFFECT: technique enables early diagnosing aiming at preventing the disease progression, thereby preventing an increase of the primary hypertension incidence by analysing two heart signals.3 cl, 9 dwg, 2 ex
Differential diagnostic technique for cardiogenic myocardial ischemia and anorectal cardioinhibitory reflex // 2535623
FIELD: medicine.SUBSTANCE: recording ECG is followed by a perianal block with an anaesthetic solution in an amount of 10.0-15.0 ml. Then 60-90 min later ECG is recorded once again, and this recording is compared to the pre-block recording. If observing a positive dynamics of the ECG results, ischemia caused by the anorectal cardioinhibitory reflex is diagnosed. No positive dynamics observed enables diagnosing cardiogenic myocardial ischemia.EFFECT: method makes it possible to perform the more accurate differential diagnosis of the above pathologies by following a specific procedure in case of pain syndrome in the given category of patients.1 ex
Differential diagnostic technique for cardiogenic myocardial ischemia and enteral cardioinhibitory reflex // 2535621
FIELD: medicine.SUBSTANCE: recording ECG is followed by a bilateral translumbar block with an anaesthetic solution in an amount of 120-140 ml from each side. Then 60-90 min later ECG is recorded once again, and this recording is compared to the pre-block recording. If observing a positive dynamics of the ECG results, ischemia caused by the enteral cardioinhibitory reflex with underlying intraluminal intestinal hypertension is diagnosed. No positive dynamics observed enables diagnosing myocardial ischemia caused by a cardiac pathology.EFFECT: enabling performing the more accurate differential diagnosis of the above pathologies by following a specific procedure in case of pain syndrome in the given category of patients.1 ex

ethod of increasing accuracy in measurement of coordinates of myocardium signals and device for its realisation // 2535439
FIELD: medicine.SUBSTANCE: group of inventions relates to medical equipment. In the method realisation ECG graphs and graphs of tracks of coordinates of the heart electric activity source are built in the system of coordinates, connected to electrodes on the patient's body. After that, the time "zone of beginning" of a P/Q impulse is identified. In the "zone of beginning" a time ECG track is approximated and an intersection of an approximated curve with an isoline is found to determine the time moment of the point of P/Q "beginning". The determined time moments of the "beginning" points are transferred onto an initial track of impulses. The origin of the myocardium coordinate system is transferred into the determined point P of the track. Coordinates of the sinus node of the myocardium SU are tied to the track origin for the complex P, and those of the interventricular septum IVS - to the track origin for the impulse Q. The device for the method realisation contains an electrocardiograph, a unit for the identification of the time area of the "beginning" of the impulse P/Q, a unit of fixation of the "beginning" point on the graph of the tracks and a unit of transfer of the primary system of coordinates into the myocardium coordinate system.EFFECT: group of inventions makes it possible to increase the efficiency of electrocardiographic examination due to an increased accuracy in the measurement of coordinates of the heart electric activity source.2 cl, 5 dwg

ethod for clinical prediction of probability of suffered silent stroke in patients with arterial hypertension // 2534865
FIELD: medicine.SUBSTANCE: patient is tested to determine clinical characteristics, each of which is scored to calculate a diagnostic index. The following clinical characteristics are determined: arterial hypertension taking into account its stage and length; diabetes mellitus, its length taking into account the patient's age and complications; ischemic heart disease and its length, cardiac angina, myocardial infarction and its length; the patient's age; compliance; smoking. The absence of any of the above characteristics is scored as 0 points. That is followed by calculating the total score; depending on the derived value, a high, moderate or low probability of the suffered silent stroke is predicted.EFFECT: method enables establishing the presence of the suffered silent stroke reliably.3 dwg, 4 tbl, 3 ex

Diagnostic technique for risk of developing stress-induced pitted keratolysis // 2533732
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to physiology and dermatovenerology, to diagnostic technique for a risk of developing pitted keratolysis accompanied by stress as an uncurable element of the professional environment for the purpose of the goal-oriented prevention of the above disease in the individuals having hazardous occupations. A heart rate variability is examined twice - before and 15 minutes after a hot test on a plantar surface. If observing no decrease of the LF/HF value as compared to the reference, a risk of developing stress-induced pitted keratolysis is diagnosed.EFFECT: technique provides more accurate diagnosis of a risk of developing stress-induced pitted keratolysis by examining the heart rate variability and using the hot test.1 dwg, 2 tbl, 2 ex

Device for suppressing power-frequency noise effect on electric cardiosignal // 2532297
FIELD: medicine.SUBSTANCE: invention refers to medical equipment. A device for suppressing a power-frequency noise effect on an electric cardiosignal comprises a TR-segment time domain selection unit (2), a key element (8), a filter (14), an amplifier (15), a delay unit (16) and a subtract unit (17). An input of the device is connected to the first input of the key element and an input of the delay unit; an output of the device is an output of the subtract unit. The device comprises an electric cardiosignal second derivative forming unit (1), a comparator (3), an RS-trigger (4), an AND circuit (5), a binary counter (6), a decoder (7), second (9), third (10), fourth (11) and fifth (12) key elements and a scaling amplifier (13).EFFECT: using the invention enables the higher noise resistance of the analysed electric cardiosignal without misrepresenting information components.8 dwg
 
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