Human necessities (A)

A            Human necessities(312810)
Substituted 2-(1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-3-phenyl-1h-1,2,4-triazol-5-yl)propanoic acids and method for their production // 2645683
FIELD: pharmacology.SUBSTANCE: invention relates to 2-(1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-3-phenyl-1H-1,2,4-triazol-5-yl)propanoic acids of general formula I where R=NO2 (Ia - 2-(3-(4-nitrophenyl)-1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-1H-1,2,4-triazol-5-yl)propanoic acid; R=OCH3 (Ib - 2-(3-(4-methoxyphenyl)-1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-1H-1,2,4-triazol-5-yl)propanoic acid; R=CH3 (Ic - 2-(3-(4-methylphenyl)-1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-1H-1,2,4-triazol-5-yl)propanoic acid; R=H (Id - 2-(1-(3-oxo-3,4-dihydroquinoxalin-2-yl)-3-phenyl-1H-1,2,4-triazol-5-yl)propanoic acid. The invention also relates to a method for their preparation.EFFECT: new compounds are obtained that can be used as antimicrobial agents.2 cl, 2 tbl, 5 ex
ethod for producing 7-substituted 4,4-dimethyl-9-oxo-4,4a-dihydro-9h-xanten-2-carbonic acids and their cytotoxic activity // 2645679
FIELD: chemistry.SUBSTANCE: invention relates to the method for producing 7-substituted 4,4-dimethyl-9-oxo-4,4 and-dihydro-9H-xanten-2-carboxylic acids of the general formula (I) , where: R=CH3O (Ia); R=CH3 (Ib); R=H (Ic); R=Br (Id); R=CL (Ie), by reacting 6-substituted 3-(4-oxo-4H-chrome-3-yl) acrylic acids, where the substituents have the above values, with enamine N-(2-methylprop-1-enil) pyrrolidine at a temperature of 20 to 80°C for 0.5 to 4 hours in the presence of a catalyst of lanthanum nitrate (III) in an amount of 0 to 20 moll. % in a medium of the solvent selected from dichloromethane, ethyl acetate, or acetonitrile and N-(2-methylprop-1-enil) pyrrolidine is used in 10-100% excess, relative to acrylic acids, followed by crystallization of the target product upon acidification of the reaction mass.EFFECT: reduction of process time, simplification of the technology of isolation of target compounds exhibiting a cytotoxic activity.2 cl, 1 tbl, 6 ex
Derivatives of 7-oxo-1,6-diazabicyclo[3.2.1]oct-3-ene, useful for bacterial infections treatment // 2645678
FIELD: chemistry.SUBSTANCE: invention relates to the field of organic chemistry, namely a heterocyclic compound of formula (Ia), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, where R1 is -CONR'R'' or -CN; R2 and R3 are independently selected from H, C1-C6alkyl, C3-C6cycloalkyl; where alkyl in the definition of R2 or R3 independently and optionally substituted with -OH, C1-C3alkoxy, -NR'R'', -C(O)NR'R'' or -NR'C(O)R''; and each of R' and R'' is independently selected from hydrogen, C1-C6alkyl, 6-membered saturated heterocyclyl containing one heteroatom N; wherein each alkyl and heterocyclyl are optionally and independently substituted with -C(O)(C1-C6alkoxy) or -NH2; provided that R2 and R3 are not both hydrogen. Invention also relates to particular compounds, a pharmaceutical composition based on a compound of formula (Ia), its use and method of treating a bacterial infection based on the use of a compound of formula (Ia). .EFFECT: technical result: new diazabicyclooctene derivatives, useful in the treatment of bacterial infection, were obtained.15 cl, 31 ex

Glucosylceramide-synthase inhibitors // 2645675
FIELD: pharmacology.SUBSTANCE: invention relates to glucosylceramide synthase (GCS) inhibitors of formula ,as well as to a method for treatment with these compounds.EFFECT: new compounds are obtained which can be used to treat a disease of lysosomal accumulation, wherein the said lysosomal accumulation disease is the result of a defect in the glycosphingolipid pathway.33 cl, 20 dwg, 1 tbl, 127 ex
Derivatives of 2,5-dioxoimidazolidine-1-yl-3-phenylurea as modulators of formylpeeptitide receptor 1 (fprl-1) // 2645673
FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry, namely to 2,5-dioxoimidazolidin-1-yl-3-phenylurea derivative of formula (I) or its enantiomer, diastereomer or pharmaceutically acceptable salt, where R1 is halogen or hydrogen; R2 is halogen, C1-8 alkyl, OR9, CN or SR15; R3 is hydrogen or C6-10 aryl; R4 is C1-8 alkyl, , , , , , C3-8 cycloalkyl or together with R5 forms a spiro-monocyclic or bicyclic carbocyclic saturated or partially unsaturated 5- to 10-membered ring; R5 is C1-8 alkyl optionally substituted with phenyl which is optionally substituted Cl, F, OH, F and OH, -(COOMe) or -COOH; furan, methylfuran, thiophene, pyridine, indole or OH; C3-8 cycloalkyl, ethylindole or together with R4 forms a spiro-monocyclic or bicyclic carbocyclic saturated or partially unsaturated 5- to 10-membered ring; R6 is halogen or hydrogen; R7 is hydrogen; R8 is halogen or hydrogen; R9 is C1-8 alkyl; R15 is C1-8 alkyl; R17 is hydrogen, C6-10 aryl or C1-8 alkyl optionally substituted with methoxyphenyl; R18 is hydrogen or C1-8 alkyl substituted OH, CO2t-Bu, COOH or CONH2; R19 is C1-8 alkyl substituted with OH; each R20 is independently selected from hydrogen or C1-8 alkyl; R21 is hydrogen; n is 1 or 2; m is 1 or 2; and including the following compounds: and ; with the proviso that the compound of formula I does not have the structure indicated in claim 1. Invention also relates to pharmaceutical composition based on the compound of formula I. .EFFECT: new 2,5-dioxoimidazolidine-1-yl-3-phenylurea derivatives useful as modulators of N-formylpeptide receptor 1 (FPRL-1) have been obtained.12 cl, 11 tbl, 17 ex

New compounds of pyrrolopyrimidine as inhibitors of protein kinases // 2645672
FIELD: pharmacology.SUBSTANCE: invention relates to new pyrrolopyrimidine derivatives of the general formula (VIII) having the properties of a cell proliferation inhibitor mediated by the activity of EGFR, BLK, BMX / ETK, BTK, FLT3 (D835Y), ITK, JAK1, JAK2, JAK3, TEC, or TXK kinase, that can be used to treat and/or prevent a proliferative disorder, cancer or tumour associated with the activity of the said kinases. Such diseases can be represented by sarcoma, squamous cell carcinoma, fibrosarcoma, cervical cancer, stomach cancer, skin cancer, leukemia, lymphoma, lung cancer, non-small cell lung cancer, colon cancer, CNS cancer, melanoma, ovarian cancer, kidney cancer, prostate cancer, breast cancer, liver cancer, head and neck cancer and pancreatic cancer. In the general formula (VIII) X1 is O or NH; R1 and R2 are hydrogen; n is 0; R4 is selected from hydrogen, C1-6alkyl, C3-7cycloalkyl and -NR22R23; where alkyl or cycloalkyl is unsubstituted or substituted by hydroxyl or amino; and where each R22 and R23 are independently selected from hydrogen and C1-6alkyl or R22 and R23 can be combined to form a 3 to 10-membered ring; R5 is hydrogen; R6 is selected from hydrogen and C1-6alkoxy; R7 is selected from hydrogen and C1-6alkoxy; R8 is selected from hydrogen and halogen; Q is a CR9 or N; R9 is selected from hydrogen, halogen and C1-6alkyl; R11 is hydrogen; R12 is selected from hydrogen and C1-6 alkyl; R13 is selected from hydrogen, C1-6alkyl, C1-6acyl, SO2-C1-6alkyl and C3-7cycloalkyl, wherein each alkyl is unsubstituted or substituted by hydroxyl or halogen; and -NR18R19 is or , where R10 is selected from hydrogen and C1-6 alkyl; R15 is unsubstituted methyl or represents C2-4alkyl, unsubstituted or substituted by halogen; and m is 1 or 2; or R19 and R9 taken together, form a 5- or 6-membered heteroaryl ring optionally substituted by C1-6alkyl which is unsubstituted or substituted by amino; and R18 is hydrogen or C1-6alkyl or absent to satisfy the valency of the heteroaryl ring.EFFECT: improved compounds properties. 29 cl, 23 dwg, 24 tbl, 9 ex

Dishwashing machine // 2645666
FIELD: personal use and household items.SUBSTANCE: dishwasher comprising of a tank, a door, a container, a grate, a spray bracket, a water guide including a flow channel for moving water for washing from the container, and a supply port, formed in the flow channel, a delivery unit including a support member for receiving water for washing, a connection tube extending from the support member to the spray arm, and a spray arm connector, and a connecting element including a connecting element connected to the water guide and the support element and a hole formed in the connecting element. Delivery unit includes a backwards projecting mounting portion, and a connecting element includes projections spaced apart from each other to form a mounting area for the projecting mounting site so that the supply unit is connected to the water guide when the projecting mounting portion is inserted into one of the mounting areas.EFFECT: invention describes a dishwasher.27 cl, 20 dwg

Assembled sprinkler // 2645664
FIELD: manufacturing technology.SUBSTANCE: sprinkler comprising a housing having an inlet, an outlet and an inner passage extending from the inlet to the outlet, wherein the internal channel defines the longitudinal axis of the sprinkler and the nominal K-factor of at least 14.0 gpm / (psi)½; sealing assembly disposed in the outlet opening to close the sprinkler outlet; fluid deflecting member remote from the outlet opening to a first axial distance, wherein fluid deflecting member is spaced from the outlet opening to a second axial distance; heat-sensitive rapid actuation trigger located and axially aligned along the sprinkler axis between the sealing assembly and the deflecting element, wherein the starting mechanism has a nominal thermal sensitivity and a nominal temperature threshold; and two frame arms extending distally from the body disposed around the heat-sensitive trigger mechanism and supporting the fluid-deflecting member at a distance from the outlet and the inlet, wherein each arm of the frame defines the surface profile in such a way that, thermal trigger is configured to operate on an activation event with a nominal thermal sensitivity and at a nominal temperature threshold, regardless of the activation event place of origin around the sprinkler axis. At that, each arm of the frame has a first section, passing parallel to the axis of the sprinkler, and a second section extending towards the axis of the sprinkler, wherein the first section having a side surface and a medial surface with respect to the axis of the sprinkler, wherein the first sections of the frame arms define cross sections, which are asymmetric with respect to each other with respect to the first plane bisecting the body, wherein in the first plane, the axis of the sprinkler is located; and wherein each cross-section is asymmetric with respect to a second plane intersecting the first plane and perpendicular thereto, wherein the axis of the sprinkler is located along the intersection of the first plane and the second plane, wherein the lateral surface of each first section comprises a waviness.EFFECT: sprinkler device is proposed.39 cl, 11 dwg
Simulator for development of muscles of upper limbs // 2645663
FIELD: sport.SUBSTANCE: invention relates to sport training devices. Simulator contains two cylinders of bilateral action, filled with working fluid, the rods of which are rigidly connected to each other by a slider and with reciprocating pistons moving back and forth by means of a lever equipped with a replaceable handle. Also in the hydraulic system is introduced a crane valve, a connecting pump and a tank with capacities of the hydraulic distribution channel with the formation of feedback for the redistribution of the working fluid.EFFECT: technical result, to which the invention is aimed, is the increase in the efficiency of the simulator.3 cl, 5 dwg

Toilet block // 2645661
FIELD: human vital needs satisfaction.SUBSTANCE: fixing unit of a toilet unit is provided; it includes a fixing element adapted to be attached to the wall, and a sealing element. The fixing element includes a flange for fastening to the wall and a section with a tight fit, extending inward from the flange for fastening to the wall. When a fixing element is attached to a wall, a channel is formed between the wall and the portion with a tight fit. The sealing element includes a receiving portion comprising a groove formed therein and a convex portion that is disposed in the channel of the fixing member.EFFECT: improved service reliability.11 cl, 10 dwg
Non-motorized wheelchair with a direct chain drive for use as a light city vehicle, for paralympic sport, for tourism // 2645660
FIELD: personal use and household items.SUBSTANCE: invention is non-motorized wheelchair with a direct chain drive for use as a light city vehicle, for paralympic sport, for tourism. Device consists of a frame, two leading bicycle wheels, one or two support wheels, two sets of chain drives, driven by special handles with combs, which transmit the effort of the human hand directly to the chain in both directions of motion strictly along the chain.EFFECT: it provides increased mobility, the ability to use the human muscle effort, in practice, by 100 %, which allows you to achieve greater speed, also, the device is extremely easy in operation.1 cl, 2 dwg

Cardiac massage device with simultaneous artificial ventilation, cardiac activity monitoring in persons with severe forms of heart failure // 2645658
FIELD: medicine.SUBSTANCE: device refers to medical equipment, namely to a device for cardiac massage with simultaneous artificial ventilation, cardiac activity monitoring in persons with severe heart failure. The device contains a cannula for transthoracic injection connected to a two-channel distributor. The device includes two elastic chambers connected to each other via the cannula, made of hermetic biocompatible material. The chambers have an identical volume. One of the chambers is placed with a possibility of transthoracic insertion in the folded state through the cannula and inflated under the pressure of the injected air to exert a pressure on the heart, the other, external, with an ability to visually control the device functioning. The device contains a flexible mask connected to the two-channel distributor. The device includes a compressor for air introduction and removal via the air ducts into the chambers and a flexible mask connected to the two-channel distributor. The device contains a two-channel distributor, connected by the air ducts to the cannula and the flexible mask. The device includes an automatic compressor control unit for air pumping into the chambers and the flexible mask via the two-channel distributor. The device includes fixing belts connected to the cannula with chambers, an automatic control unit, an autonomous power supply unit and an electrocardiograph with a possibility of device fixation on the body and connected to the flexible mask to fix the device on the head. The device contains an electrocardiograph with three electrodes for recording cardiac activity in three leads as per Einthoven, connected to the autonomous power supply unit.EFFECT: elimination of heart failure and prolonged maintenance of blood circulation with simultaneous monitoring of cardiac activity and artificial lungs ventilation.1 dwg
ethod for evaluating the effectiveness of defects in the implementation of ambulator stomatological interventions // 2645657
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely, to dentistry. Patient and the doctor fill the analogue-visual percentage scale of pain intensity during dental surgery. Descriptors for the patient: "no pain", "weak pain", "severe pain", "very strong pain", "unbearable pain". Descriptors for the physician taking into account the pulse, blood pressure and EOD: "the clinical effect of anesthesia is expressed in full", "the clinical effect of anesthesia is close to the maximum", "the clinical effect of anesthesia is poorly expressed", "the clinical effect of anesthesia is very poorly expressed", "the clinical effect – anesthesia has not come". With a graphic mark on the patient's scale and the doctor at a level of 100 % to 90 %, the descriptors correspond to "no pain", "the clinical effect of anesthesia is expressed in full", the effectiveness of anesthesia is sufficient for painless rendering of dental care in full. With a graphic mark on the patient's scale and the doctor from less than 90 % to 80 %, the descriptors correspond to "mild pain", "the clinical effect of anesthesia is close to the maximum", the effectiveness of anesthesia is sufficient for painless rendering of dental care in full, with appropriate correction of the patient's psychoemotional state. With a graphic mark on the patient's scale and the doctor from less than 80 % to 50 %, the descriptors correspond to "severe pain", "the clinical effect of anesthesia is poorly expressed", the effectiveness of anesthesia is insufficient for painless rendering of dental care in full, the patient needs a correction of the psychoemotional state. With a graphic mark on the patient's and doctor's scale from less than 50 % to 10 % – the descriptor corresponds to "very severe pain", "the clinical effect of anesthesia is very poorly expressed", the effectiveness of the anesthesia performed is not sufficient for painless rendering of dental care, dental intervention can not be performed in full because of severe pain syndrome accompanied by both a violation of the patient's psychoemotional state and an inflammatory component at the injection site, or an unreasonable choice of the method of anesthesia and a local anesthetic drug. With a graphic mark on the patient's scale and the doctor from less than 10 % to 0 %, the descriptors correspond to "unbearable pain", and "the clinical effect – anesthesia has not come", the efficacy of the anesthesia is absent and dental interventions are impossible due to severe pain syndrome accompanied by inflammatory component at the injection site, or an unreasonable choice of the method of anesthesia and a local anesthetic drug.EFFECT: method allows simple and reliable assessment of the effectiveness of anesthesia in performing outpatient dental interventions by using the percentage score scale filled in by the doctor and patient and evaluating the most significant indicators.1 cl, 1 dwg, 5 ex
ethod for surgical access to carotid and subclavian arteries during simultaneous interventions for single atherosclerotic lesion // 2645656
FIELD: medicine.SUBSTANCE: access is formed under general anesthesia, when performing simultaneous carotid endarterectomy and subclavian-carotid transposition or carotid-subclavian artery bypassing. A cut is made from the sternoclavicular joint to the mastoid to dissect the skin, subcutaneous tissue and m.platisma. In the upper third of the wound, the sternocleidomastoid muscle together with the internal jugular vein are withdrawn outwards by a retractor. The distal common carotid artery, external and internal carotid arteries are selected. In the lower third of the wound, legs of the sternocleidomastoid muscle are separated by a retractor. If necessary, the omohyoid muscle is dissected at the tendon level after preliminary tack-up suture application. The anterior scalene muscle with the phrenic nerve and the internal jugular vein is withdrawn outwards. The first segment of the subclavian artery, vertebral artery and internal thoracic artery are isolated and tacked. At the first stage, subclavian-carotid transposition is performed, at the second - carotid endarterectomy from ICA.EFFECT: method provides simultaneous execution of operations in case of ipsilateral lesion with simultaneous correction of failure in the carotid and vertebrobasilar basins due to access to the subclavian and carotid arteries.2 cl, 9 dwg

ethod for combining segments of a smoking article and combiner for combining such segments // 2645653
FIELD: tobacco industry.SUBSTANCE: invention relates to a method for combining segments of a smoking article and combiner for combining such segments. Method for combining segments of a smoking article, comprises the steps of providing a group of segments, having a heat source and an aerosol-forming substrate, the aerosol-forming substrate which are coaxially arranged in that sequence along a common central longitudinal axis, aerosol-forming substrate is arranged such that a remote end thereof faces away from the heat source while a near end thereof abuts the heat source; feeding an airflow directing truncated hollow cone, having a widest end and a truncated narrowest end such that the truncated narrowest end is arranged to face the remote end of the aerosol-forming substrate, with a central longitudinal axis of the truncated hollow cone (13; 23) being aligned with the common central longitudinal axis of the group of segments; and moving the truncated hollow cone towards the remote end of the aerosol-forming substrate to abut the remote end thereof or to extend into an indentation in the remote end of the aerosol-forming substrate.EFFECT: technical result of the invention is a method and an apparatus for efficient and reliable combining segments of a smoking article.16 cl, 6 dwg

Charged cassette for electronic cigarettes // 2645650
FIELD: tobacco industry.SUBSTANCE: invention relates to the magazine intended for storage and recharging of electronic cigarettes, which includes: first handset that has essentially a cylindrical shape, and formed the open end of the tube location hole electronic cigarettes in the specified storage tube; charging mechanism of electronic cigarettes located inside the aforementioned first tube; the indicator light, designed to indicate the State of charge of the electronic cigarette, which is the first tube, and located at the open end of the first tube beside a hole for storage of electronic cigarettes in the first tube.EFFECT: providing charge indication.20 cl, 8 dwg, 1 tbl

Integrated basement ventilation apparatus // 2645648
FIELD: electrical equipment; ventilation.SUBSTANCE: present invention relates to an integrated basement ventilation apparatus. It comprises: an air supply fan installed in an air supply inlet of each floor of a basement structure; air exhaust fan installed in an air exhaust outlet in each floor toward an air exhaust shaft of the basement structure; plurality of connecting fans, installed on a ceiling of each floor of the basement structure; and a controller receiving electrical signals from sensors uniformly distributed in the ceiling of each floor of the basement structure for generally controlling of fans; air supply fan and the air exhaust fan include a cylindrical fan supported in a polygonal column-shaped frame, at least one of the air supply fan and the air exhaust fan is additionally provided with a fire-fighting damper which is opened or closed depending on whether the fan operates or not and which can be forcedly closed through a temperature-dependently operated fuse, at least one of the air supply fan and the air exhaust fan is additionally provided with spray nozzles which suck in water by means of negative pressure generated due to the air blowing to finely spray the water. In particular, the present invention can remarkably improve condition and maintenance of whole facilities by significantly enhancing air quality of the basement structure as well as being capable of extinguishing fire at an early stage.EFFECT: thus, the present invention can control an increase in temperature within a basement structure at a low cost and improve fire safety by preventing fire from spreading to other floors.8 cl, 12 dwg

Smoking products and other outstanding product flow // 2645647
FIELD: tobacco industry.SUBSTANCE: outstanding product flow for feeding gas flow into the mouth of a user provides a passageway for the flow and flow driven RLC site decorated with possibility of excitation of vibration under the effect of flow on the specified aisle, to transmit tactile effects to the user and contains the chassis, moveable element and connecting element for attaching a mobile element to the chassis and the transmission of vibrations from the rolling element and the source of the inhaled substance; when this resonant node in the longitudinal direction is separated and located downstream from the source of inhaled substances.EFFECT: transfer of tactile effects to the user throughout the inspiratory without having to perform any additional actions and conditions other than the usual delays and substantial increase dimensions products and minimizing delays between tightening torque and the emergence of a smoker the feeling of vibrations.20 cl, 14 dwg

Compression mask for postoperative cooling patient's soft facial tissue // 2645646
FIELD: medicine.SUBSTANCE: invention relates to a medical technique, namely to a compression mask for post-operative cooling of the soft tissues of a patient's face. Mask body with slots for the eyes, mouth and nose of the patient is made of 0.5–2.0 mm thick from a biocompatible and non-toxic polymeric material. Configuration of the mask body is modeled on the results of a pre-made computed tomography, a 3D photographic image of the patient's soft tissue, and also on the basis of the model created and produced using printing on a 3D printer with the boundaries of the postoperative area of the patient's face soft tissues. Mask is equipped with the means of fastening and fixing it on the head of the operated patient in the form of an elastic fastening strap, which is regulated by the degree of compression pressure on the surface of the soft tissues of the patient's face. Inner body surface of the compression mask is equipped with a cooling system of the surface of the operated patient's face soft tissues. Cooling system is made in the form of a continuous and curved mask placed vertically on the inner surface of the body without intersecting the serpentine branches with rounded passages of the cooling tube with the supply inlet and outlet of the cooling liquid or gaseous. Cooling tubes are made of biocompatible and non-toxic polymeric tubular material with an outer diameter of 2–3 mm with the distances between two adjacent branches of the cooling tube from 5 to 8 mm.EFFECT: technical result is reliable provision of the given immobilization, cooling and maintenance of the operated tissues.5 cl, 2 dwg
ethod of forecasting improvement of physical functioning as a parameter of quality of life in patients with ischemic heart disease in one year after coronary bypass operation // 2645645
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiology. To forecast the improvement in physical functioning, IHD patients are given a six-minute walk test to assess the depression on the hospital anxiety and depression scale, presence / absence of akinesis based on echocardiographic test is identified. Prior to coronary bypass surgery, the probability of improving of physical condition as a parameter of the quality of life is determined, one year after the coronary bypass surgery using the formula where p is the probability of improvement of physical condition; e is the base of the natural logarithm (e = 2.718); f is the value of the discriminant function, which is determined by the equation, ƒ=-2.325+0.005x1+0.15x2-1.007x3, where 2.325 is constant; 0.005; 0,15; 1,007 are weights of the corresponding indicators; x1 - the number of meters walked during the six-minute walk test; x2 - the number of points on the hospital anxiety and depression scale; x3 - presence / absence of akinesis, determined by the results of echocardiographic test: x3= 0 - in the absence of akinesia, x3= 1 - in the presence of akinesia. If p is > 0.58, the improvement in physical condition is predicted one year after the coronary bypass surgery.EFFECT: method makes it possible to predict the probability of improvement of physical condition one year after the coronary bypass surgery to select the way of managing each particular patient.1 cl, 1 tbl, 2 ex
ethod for predicting the course of the initial choroidal melanoma // 2645644
FIELD: medicine.SUBSTANCE: invention relates to medicine, specifically to ophthalmology. To predict the course of the initial choroidal melanoma, before the treatment, optical coherence tomography is performed, the area and volume of exudate over the tumor are determined. With an exudate volume of more than 65.7 mm3 and area – more than 5.26 mm2 a heavy course id predicted.EFFECT: method allows to predict the course of the initial choroidal melanoma in the early stages of the disease by identifying specific parameters that affect the course of the disease, for planning an adequate organ preservation treatment.1 cl, 2 ex
ethod for laparoscopic cholecystectomy // 2645643
FIELD: medicine.SUBSTANCE: in case of cholecystectomy from laparoscopic access, pressure of 5 to 8 mm Hg is created in the abdominal cavity. An additional 10 mm trocar is installed for liver retraction with subsequent clipping of the artery and duct in the Kalo triangle and cholecystectomy. The installation of an additional trocar creates conditions for traction of the liver or duodenal ligament bringing it down with reduced pressure in the abdominal cavity. The bladder duct and artery in the region of the Kalo triangle are visualized. The duct and artery are isolated and clipped. Hemostasis is performed and bile leakage from the duct during operation is controlled.EFFECT: method allows to improve the results of laparoscopic cholecystectomy in patients with cardiovascular pathology, reduces the risk of postoperative and/or intraoperative cardiovascular complications, with a minimal risk of damage to neighbouring organs.2 ex
Transligent-patellar operative access to the knee joint of small cattle (sheep) // 2645642
FIELD: veterinary science.SUBSTANCE: invention relates to the field of veterinary medicine and is intended for use in operative access to the knee joint of a sheep. Sheep in position on the side is fixed to the operating table. Lower third of the thigh and the upper third of the shin of the sheep's limb, on which the surgical procedure is performed, is cut, the assistant holds it in the bending position. Surgical access zone is treated with an antiseptic. Along its own patellar ligament, starting from its lower corner to the tuberosity of the tibia, an incision of the skin of 3 cm long is performed. Next step is the dissection of subtle subcutaneous fat, providing access to its own patellar ligament. Own patellar ligament is extended all over. Edges of the ligament are separated and fixed. Dissecting part of the fat body, creating a "floating window", with the displacement of which medial condyle is medially visible, and with lateral displacement is the lateral condyle.EFFECT: method allows for safe operative access to the knee joint for visualization of both hip condyles.1 cl, 4 dwg
ethod of orthodontic treatment of patients with defects of hard teeth tissue // 2645641
FIELD: medicine.SUBSTANCE: invention relates to medicine and may be used to temporarily replace total and subtotal defects of the crown part of the teeth in cases where it is necessary to install a bracket for orthodontic treatment. Get imprints. Make models. Simulate anatomical form using wax. Positioning and fixing of the orthodontic bracket is performed at the stage of modeling the crown from wax. Braces are installed on the vestibular or oral surface of the tooth. Support area of the bracket is covered with an additional layer of wax, which is replaced by polymerization with plastic. Supporting tooth with wax reproduction of the artificial crown is gypsum plated in a cuvette and placed in boiling water for 10–15 minutes, and then opened. For the production of plastic crowns, plastic is used. Ready-made temporary plastic crown with a bracket installed in it is fixed to the stump of the supporting tooth.EFFECT: method allows to increase the effectiveness of orthodontic treatment in patients with total and subtotal defects of hard tissues, as well as to prevent the destruction of hard tooth tissues due to the carious process.1 cl, 6 dwg, 2 ex
ethod for predicting potential efficacy of endoscopic treatment of vesicoureteral reflux // 2645640
FIELD: medicine.SUBSTANCE: invention relates to medicine, surgery. Predict the effectiveness of endoscopic treatment of vesicoureteral reflux in children. At the mouth of the ureter, a ureteral catheter with a measuring scale is inserted through the working channel of the cystoscope. Cystoscope is deflected axially upwards relative to plane of operating table by no more than 20°. Model the endoscopic correction of the shortening of the submucosal ureter. Deformation of ureteral anterior wall is visually determined when end of catheter is moved from intramural to submucosa. Determine the length of the submucosa of the ureter. Length of no more than 2 mm is regarded as adverse predictor of the effectiveness of endoscopic treatment.EFFECT: method for predicting the potential efficacy of endoscopic treatment of vesicoureteral reflux is proposed.1 cl, 2 dwg, 3 tbl
ethod of ultrasound-assisted blockade in arthroscopic surgical interventions in the shoulder joint // 2645639
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to anaesthesiology. Patient takes the chosen position. Long-axis ultrasound scan with a linear sensor of 8–12 MHz is performed with the separation of the suprapatropic artery and nerve. Needle with an anesthetic is entered with the needle point running to the suprathiopathic nerve and the anesthetic is administered. In this case, the patient is placed in a prone position on a healthy side. Scanning is performed in the region of the superspinous fossa of the scapula, slipping ventral until the incisure of scapula is verified in the ultrasound scanner, after which the sensor is moved from the area above the incisure of the scapula back to the superspinous fossa, with a simultaneous ventral inclination and the location of the scanning plane of the sensor in the superspinous fossa near the incisure of the scapula. As a needle, a neurostimulation needle is used, injection is medial to the sensor. As an anesthetic, a solution of ropivacaine is administered, after which, without changing the position of the patient, the sensor is transferred to the horizontal plane and the place of divergence of the posterior circumflex humeral artery from the axillary artery and the axillary nerve is identified. Needle is entered lateral to the sensor along the long axis in the ventromedial direction. Solution of ropivacaine is administered until the appearance of hypoechogenic shadows around the nerve and the cessation of contractions of the deltoid muscle. As an anesthetic, at each injection, 5 ml of 0.75 % ropivacaine is administered. Blockade is supplemented by general anesthesia with intubation of the trachea using sevoflurane.EFFECT: method allows to reduce the risk of serious complications and prevent the risk of compression-ischemic neuropathy of the suprathinus nerve, method does not affect hemodynamics, does not cause motor blockade of the limb below the shoulder joint, which allows an early evaluation of traction complications.3 cl, 3 ex, 10 dwg

anual electrical skin care device // 2645637
FIELD: medicine.SUBSTANCE: invention relates to medical equipment. Hand-held electrical device for skin care contains a base for use as a handle with the possibility of its grasping by hand, first outer electrode, which is disposed on the base outer side so that it is in contact with the hand while the device is held in the user's hand, a cap (9) mounted on the base with the possibility of removal, comprising a second outer electrode (20), which can be placed on a portion of the skin being treated, an electric power source, which poles are electrically connected to the first and second external electrodes during operation of the device, and an electrically powered vibrator (15). Vibrator contains an electric motor and a cam attached to the motor shaft. Vibrator is fixed in the cap and is configured to transmit vibrations to a device part located on the skin portion, subject to treatment, with the provision, of the intensive massage action on the skin during device operation, promoting expansion of the pores. Cap lower end is made to be mounted on the base, and the cap opposite upper end forms the second outer electrode. Motor axis and shaft extend generally parallel or transversely to the virtual line between said lower end and the second outer electrode. In the cap the bottom part is inserted, which on its one side, which is the upper side and facing the cap, contains a vibrator holding device.EFFECT: enabling intensive massage effect on the treated skin, which contributes to the expansion of the pores.20 cl, 16 dwg
ethod for prosthetics of a tricuspidal valve in patients with infectious endocarditims // 2645634
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiosurgery. They perform imposition of individual U-shaped seams on gaskets along the line of fibrous ring in projection of anterior and posterior valves, fixing prosthesis braid, pressing heart tissue against the prosthetic framework. In this case, seams begin to be stitched from anterior septal commissure clockwise from anterior valve to anterior-posterior commissure. Further on posterior leaf and, without reaching posterior septal commissure, continue suturing right atrium wall from the outer side of the coronary sinus outer side, moving it into right ventricle cavity. Then, filaments of the suture drawn just behind coronary sinus and first U-shaped suture are simultaneously stretched to form muscular bead. Subsequent U-shaped sutures are applied with capture of formed muscle roller to form a closed line, while U-shaped seams are made in steps of 5–7 mm and 1–1.2 mm. intervals between seams.EFFECT: method allows higher treatment efficiency, reduction of number of patients who need implantation of pacemaker, disability reduction of this category of patients.1 cl, 3 dwg, 3 ex
ethod of capsulotomy during arthroscopic operations on the hip joint // 2645632
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to orthopaedics and traumatology. Traction of the lower limb along the axis is performed. Anterolateral and medial arthroscopic approaches are formed. Capsulotomy of the anterior-external segment with the smooth banana-shaped knife is performed, with the formation of incisions, which are located in the staggered manner and perpendicular to the fibers of the joint capsule.EFFECT: method allows for the even relaxation of the anterior-external capsule of the joint, improvement of intraarticular visualization, and reduction of traumatism.1 cl, 1 ex

ethod of prevention of bleeding caused by the application of antiagregants, experiment stage // 2645630
FIELD: medicine.SUBSTANCE: invention relates to medicine, in particular to experimental surgery, and can be used to prevent bleeding when applying double antiplatelet therapy before surgery. To this end, a solution containing fibrin monomer at a concentration of 11 mg/ml and urea at a concentration of 150 mg/ml is given to a rabbit-male chinchilla one hour before the operation. In this case, the dose of fibrin monomer is 0.25 mg/kg.EFFECT: method is highly effective, since it not only reduces the amount of blood loss, but also is safe when applied.1 cl, 2 dwg

Form with tear-off bracelets // 2645628
FIELD: printing industry.SUBSTANCE: printable form for identifying a patient having at least one blank tear-off bracelet containing a waterproof printable nylon tufted faceplate and a backing. The face layer is stamped with a stamp to form at least one unfilled tear-off bracelet having a first end and a second end; the nylon tuft layer being 4-6 mils (0.1016-0.1524 mm) in thickness and has a coating on the upper surface and on the lower surface. The coating on the upper surface of the face layer is configured to receive printable, mutable patient data. The bracelet is waterproof, soft for the patient's hand and is configured to remain attached to the patient for a number of days without loss of the printed patient data being changed. The face layer is adhered to the substrate with a contact adhesive applied to at least a portion of the lower surface of the face layer. The contact adhesive is applied to the face layer around the periphery of at least one bracelet, leaving a portion of said bracelet between said first and second ends not adhered to the substrate. The means for securing the bracelet to the patient's wrist are located next to the first end and the second end of the bracelet. Each of the mentioned first end and a second end of each of the bracelets has means for indicating the opening.EFFECT: bracelet provides a reusable use, sufficient water resistance and can remain attached to the patient for several days without loss of the printed patient data being changed.16 cl, 13 dwg
ethod for predicting the occasional acute myocardial infarction within the five years of the post-infarct period // 2645626
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiology. Combination of factors affecting to the development of occasional acute myocardial infarction within five years of the post-infarction period is determined. In this case: the patient,with chronic cardiac failure at the time when index myocardial infarction, the need for use of long-acting nitrates for discharge from the hospital, the presence of hemodynamically significant of arterial sclerotic disease of left coronary artery, the assignment of statins in the acute period of myocardial infarction and at discharge from the hospital are determined. Probability of developing occasional acute myocardial infarction in the post-infarction period is determined by the original formula. And with a value of p ≥ 0.15 predict the development of an occasional acute myocardial infarction within five years of the post-infarction period.EFFECT: method makes it possible to predict in a timely manner the high probability of developing occasional acute myocardial infarction within five years after a previous myocardial infarction and to carry out measures to optimize therapeutic and diagnostic tactics in this category of patients in order to improve the course and fate of the disease.1 cl, 2 ex, 1 tbl
ethod of individual manufacture of exoprothesis of a nipple-areolar complex // 2645621
FIELD: medicine.SUBSTANCE: invention relates to medical prostheses and can be used to compensate for tissue deficiency in the region of the remote nipple-areolar complex (NAC) in patients who underwent surgery for the mammary gland. Method includes manufacturing of NAC from silicone. Before the operation to remove the mammary gland, a color scale in tone with the NAC is selected for the patient, a NAC cast is made, the cast is removed and, after complete drying, a two-component soft silicon on a platinum base is poured into its cavity step by step. At the first stage, the nipple cavity is cast and colored in a selected tone. On the second stage, the areolar cavity is filled and colored. Silicone filled mold is dried at room temperature for 30 minutes. Before fixing to the skin, the fixing side of the NAC exoprosthesis is covered with latex and silicone glue.EFFECT: invention makes it possible to provide a long fixation of the prosthesis to the body and to improve the quality of life of the patient.1 cl, 10 dwg

Bucket // 2645619
FIELD: personal and household items.SUBSTANCE: invention relates to the field of satisfying a person's vital needs, namely to a bucket, and can be used for transportation and storage of any materials (liquid, loose, pasty, etc.). Bucket consists of the walls, the bottom, the flange and the handle, the sides of which are designed so that in the side view they have the form of an L-shaped angle with a short and long shoulders, the handle being fixed in such a way that in the extreme upper position the outer edge of the short arm of the hand rests on flanging.EFFECT: this design of the bucket increases the consumer characteristics and ease of operation with minimal production costs.1 cl, 4 dwg

Ophthalmic lens with a passive event-based coloration system // 2645618
FIELD: medicine.SUBSTANCE: invention relates to medicine. Ophthalmic Lens with passive event coloration mechanisms comprises: a soft lens portion, wherein the soft lens portion comprises a polymerized Reactive Monomer Mixture; and an event coloration mechanism. Event coloration mechanism is capable of triggering a visual indication in the Ophthalmic Lens based on an occurrence of a predefined event. Event coloration mechanism is in contact with a portion of the soft lens portion. Moreover, the event coloration mechanism is arranged to be located within the optical zone of the lens in such a way that the activation of the coloring mechanism based on the event is visible to the lens user.EFFECT: application of this invention will allow a patient to maintain safe and effective levels of certain biomarkers.19 cl, 4 dwg
Fixation method of distal tendon of arm biceps muscle to radiai bone tuberosity // 2645616
FIELD: medicine.SUBSTANCE: invention relates to traumatology and orthopedics and can be useful for fixing distal tendon of biceps arm muscle to radius tuberosity. Form parallel channels in radius tuberosity, form through the incision of the skin on the front surface of the shoulder. Two pairs of ligature loops are carried out through meatus by means of thin conductor and are taken out to posterior forearm through a skin puncture. Meatus ligature loops are fixed by mutual crossing, then alternately drawn in opposite directions through the channels to the front surface of the forearm in such a way that the ligature loop of the first channel is removed from the second channel, and the ligature loop of the second channel is removed from the first channel. Tendon ligatures fixing the tendon are fixed to the ligature loops of the canals and again pulled through radius tuberosity meatus in the opposite direction, taking into account anatomically correct position of tendon. Tendon ligatures pulled out on the anterior surface are stretched and fixed to radial tuberosity bone through access on the anterior surface of the lower third of the arm.EFFECT: method reduces traumatization of soft tissues, prevents rotational contractures.1 cl, 1 ex, 4 dwg

Dirt collecting device and floor cleaner with such dirt collecting device // 2645615
FIELD: household appliances.SUBSTANCE: application describes a dirt collecting device for a floor cleaner, comprising carrier (22) fixed or fixable to floor cleaner (10), and also detachable holder (26) and suction bar (28) held by the latter, carrier (22) and holder (26) being fixed to each other by means of lock device (52) in a locked position, and dirt collecting device (18) comprises control element (112) transferred from the unactuated position to the actuated position for transferring lock device (52) to the unlocked position, providing the detachment of holder (26) from carrier (22). According to the invention, in order to create an easy-to-operate dirt collecting device, handle (74) is held or formed on holder (26) and/or on suction bar (28), and control element (112) in the unactuated position is located at a greater distance from handle (74) than in the actuated position in which the operator can grip handle (74). In addition, the invention relates to floor cleaners with dirt collecting device (18).EFFECT: dirt collecting device for floor cleaners is proposed.35 cl, 6 dwg

Functional toilet chair for disabled // 2645614
FIELD: human vital needs satisfaction.SUBSTANCE: toilet chair for disabled is proposed, which represents a module of interconnected parts and connections, intended for its installation on frames of equipment and furniture for disabled. The chair has curved guides, in which pivotally interconnected panels move, has an automatic function of raising and lowering of additional guides working through the drive, materials for toilet chair manufacture can be metals or metal polymers.EFFECT: as a result of the module operation, a patient with working hands, is able to vertically unlaid himself without any help, which allows him/her to lower his underwear himself in order to fulfil natural needs.3 cl, 7 dwg
ethod of tobacco dependence treatment // 2645612
FIELD: medicine.SUBSTANCE: group of inventions refers to medicine, namely to narcology, and can be used in treatment of tobacco dependence. To treat tobacco dependence in a smoker and rendering assistance to him in the refusal of tobacco-containing products without the appearance of withdrawal symptoms, they conduct conversations to educate the smoker about the shortcomings of smoking and its harmful effects, while conversation is conducted in presence of assistant. Perform a program of intensive detoxification at home (IDD), which lasts no more than 24 hours to remove toxins from the body of the smoker. And the IDD program includes compliance with prescribed dietary measures, including the intake of antioxidant natural foods. At the same time, part of the IDD program includes the step of introducing a drinking solution based on aloe vera, which contains natural aloe vera suspended in a drinking solution, while the assistant supervises the IDD program. Maintain an established diet that includes a list of antioxidant natural foods to eat with each meal, and oral hygiene, including the use of an aloe vera toothpaste, for a predetermined period after the completion of the IDD program. In this case, the administration of a drinking solution based on aloe vera is continued for a predetermined period of time and exclude the use of medicines to control the symptoms of withdrawal syndrome.EFFECT: group of inventions allows to get rid of tobacco dependence and tobacco-containing products without withdrawal syndrome symptoms due to intensive detoxification, diet and hygiene.20 cl
ethod for laparoscopic ventral hernia repair // 2645610
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to surgical methods for treating patients with ventral hernias. Introduce trocar in the left hypochondrium and on the left side of the abdominal wall. Conduct pneumoperitoneum, overview laparoscopy, dissection of adhesions, determination of the size of the hernial gates, implantation and fixation of the mesh on the abdominal wall with a hernia gate closure 3-5 cm. After dissection, the adhesions are transposed into the abdominal cavity of the hernial sac until its cavity is eliminated. Then peritoneal tissues of hernial sac are fixed along the part or along the perimeter of the hernial gates, and the mesh is additionally fixed to the peritoneum of the hernial sac.EFFECT: method reduces postoperative complications, prevents the formation of sulfur.1 cl, 2 ex, 5 dwg
ethod of efficiency control of lumber-cross radical radiaculopathia treatment, disordered by herbs of interversal discs, ultrasound-controlled epidural blockade // 2645609
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to neurology, and can be used to control the effectiveness of lumbosacral radiculopathy due to herniated intervertebral discs, ultrasound-controlled epidural blockades. On 7–10th day after beginning of treatment ultrasound survey is carried out in mode of elastography of rotation waves. As a measure, Young's module Emean of the back contour of the intervertebral disc is used. With a decrease in its value below 37.5 kPa treatment is considered effective, further treatment with ultrasound-controlled epidural blockades is stopped. With a Young's modulus of Emean above 37.5 kPa, treatment is considered ineffective and the implementation of ultrasound-controlled epidural blockades continues until the value of Young's Emean modulus is lower than 37.5 kPa. Examination of Young's module Emean after the treatment is carried out after 7 days.EFFECT: method provides high accuracy and reliability of the effectiveness control of lumbosacral radiculopathy by determining the objective elastography index.1 cl, 3 ex

Vacuum flask assembly // 2645608
FIELD: packaging industry.SUBSTANCE: invention relates to a vacuum flask assembly (1), a vacuum flask container (3) (2), and a baby bottle kit. The unit (1) of the vacuum flask contains a vacuum flask (2) with a cover (5) with a push button. The lid (5) with the push button is movable between the open state and the closed state in which the sealing switch (15) of the lid (5) is raised when the lid (5) is in its open state and retracted when the lid (5) is in its closed state. The vacuum flask assembly (1) further comprises a container hood (21) which can be positioned over the lid (5) and mounted on a vacuum flask (2). When the lid (5) is in its open state, the container part (21) is adapted to act on the sealing switch (15) when the container lid (21) is mounted on the vacuum flask (2), so that the lid (5) is forced to transfer from its open state to its closed state.EFFECT: convenience increase.14 cl, 9 dwg
ethod for preoperative determination of intra-lenticular pressure in patients with swelling cataract // 2645607
FIELD: medicine.SUBSTANCE: invention can be used for pre-operative determination of the intra-lenticular pressure (ILP) in patients with swelling cataract. Preoperative ultrasound biomicroscopy of the anterior part of the eye is performed. Lens thickness, depth of the anterior chamber and hypoechoic layer thickness are determined. The ILP is calculated by the formula: ILP=-21.940+8.082×A+4.244×B+2.800×C, where A is lens thickness; B is depth of the anterior chamber; C is hypoechoic layer thickness.EFFECT: method provides objective ILP determination in patients with swelling cataract, which allows phacoemulsification of the swelling cataract without complications.2 ex

Vacuum cleaner tool // 2645606
FIELD: personal and household items.SUBSTANCE: in the lower part of the nozzle, a suction opening is elongate and extends from a front to a rear of the nozzle. Bristle assembly is mounted within the nozzle and protrudes through the suction opening. Suction opening is delimited along its length by a leading edge and a trailing edge, and at least part of the leading edge is raised relative to a front end and a rear end of the nozzle. Such that, when the tool is swept over a cleaning surface, the front end and the rear end of the nozzle contact the cleaning surface and a gap is created between the cleaning surface and the leading edge.EFFECT: vacuum cleaner tool, including a nozzle and a bristle assembly, is offered.8 cl, 14 dwg

Plaque detection by flow probe // 2645605
FIELD: medicine.SUBSTANCE: dental device with a flow probe is provided, which configuration is such that the passage of fluid (30) through the open port (136, 2604) of the distal tip (112, 112') of the probe provides detection of the substance (116) on the dental surface (31, 33) based on the measurement of the signal correlated with the substance, at least partially impeding fluid (30) passage through the open port (136, 2604). The device (100, 100') includes a proximal pumping portion (124) and at least one distal portion (110) of the probe, configured to be immersed in another fluid (11), for example water in the toothpaste foam. At least one distal probe portion (110) may include two or more components for that.EFFECT: improvement of efficiency and reliability.4 cl, 41 dwg, 1 tbl
ethod for rehabilitation of motor disorders // 2645604
FIELD: medicine.SUBSTANCE: invention relates to medicine, specifically to neurology, and can be used in rehabilitation measures in patients with motor disorders. Versions of the method of rehabilitation by means of conducting physical therapy sessions with feedback are disclosed. In the first version, feedback in the process of exercise therapy is carried out by means of partial immersion of the subject in a virtual environment by means of a non-contact infrared sensor, while on the screen of a monitor a third person immersion is created in front of the subject, specifically the visibility of the repetition of movements by the character, performed by the subject in reality. In the second version, feedback is carried out by completely immersing the subject in a virtual environment through virtual reality glasses or a virtual reality helmet or a room with panoramic screens, while in front of the subject the effect of immersion from the first person is created. Session is divided into 3 parts first – exercises aimed at restoring the motor function of the hand, second – movements, aimed at restoring the motor function of the leg and static balance, third – exercises aimed at restoring coordination of the upper and lower extremities in space. During the physical therapy exercises, the level of the patient's initial motor activity is assessed by drawing the arm to the side with the maximum possible amplitude, raising the arm in front of the patient with the maximum possible amplitude, leading and bringing the raised hand to the sides to determine the right and left boundaries, the maximum possible flexion and extension of the arm in the elbow joint, flexion of the hip and knee in front of the patient with the maximum possible amplitude, moving the leg to the side with the maximum possible amplitude, tilting the body to the right and left, forward and backward, taking it as 100 %. Upon its achievement during the exercise, the required level of activity is raised by 10 % or more relative to the initial level, thereby realising virtual sensory stimulation. Duration of one session of therapeutic exercise is no more than 45 minutes.EFFECT: method provides effective restoration of motor activity due to enhanced virtual feedback through immersion in virtual reality, from both the third and first person, and the use of a virtual environment for targeted motor training.2 cl, 2 ex

Detection of gum using optical detector in oral hygiene detection device // 2645603
FIELD: physics.SUBSTANCE: detection device (1000) allows to detect a substance (116) that may be present on the surface (31, 33), on the basis of the stream probe signal measurement, correlating with the substance (116) at least partially preventing the passage of fluid (30, 35) through the stream probe (500). The device includes a distal section (620) of the optical gum detector transmission and a distal section (720) of the optical gum detector reception in the position for transmission and for reception, respectively, of the optical signal under the control of the controller (2251), allowing the controller (2251) to determine whether the open port (526) of the distal end (522) of the stream probe (500) contacts with the substance (116) at least partially preventing the passage of fluid (30, 35) through the open port (526), and whether it contacts with the gums of the subject or the user of the detection device (1000) to ignore the false positive signals.EFFECT: device improvement.28 cl, 46 dwg
ethod of restoration of integrity of the rear spinal complex in the case of acute resectional laminectomy // 2645602
FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly to spinal surgery. They perform distraction and reclamation in injured vertebral-motor segments with the help of a transpedicular design established above and below the resected area. They apply a thin layer of Bio Glue two-component adhesive to the bare part of the dura mater. Titanium mesh, modeled according to the shape of the spinal canal, is placed on the bone defect, it is placed under the heads of the pedicle screws with grooves formed on the share sides.EFFECT: method stabilizes the spine and prevents adhesion in the epidural space.1 cl, 1 ex

Damper for smoking device // 2645601
FIELD: tobacco industry.SUBSTANCE: portable damper device for extinguishing one smoking article at one time contains an external container; inner sleeve; a hole of such a size that it allows one smoking article to be placed in the inner sleeve; and a cover for closing the absorber, the inner sleeve being inside the outer container and at least partially detached from the outer container, at least one slot extending substantially along the entire length of the inner sleeve is formed in the inner sleeve to allow passage of the fluid between the inner sleeve and the outer container so that the fluid can freely flow between the inner sleeve and the outer container during normal operation of the absorber and the lid, when closed, prevents release of fluid medium from the damper.EFFECT: providing increased heat dissipation and reduced damping time.14 cl, 6 dwg

Needle-protection device for medical instruments // 2645600
FIELD: medicine.SUBSTANCE: device is movably located on the needle and contains the first part and the second part. At that, the said first part comprises a base section, a middle section and an upper section forming the first lever; and the said second part comprises a base section, a middle section and an upper section forming a bent second lever. The said base section of this first part and this second part is configured to remain in a retaining relationship with the inner periphery of the catheter housing of the said catheter node IV prior to use.EFFECT: improved protection against accidental pricks with the needle tip.16 cl, 7 dwg
 
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